Ashy dermatosis with involvement of mucous membranes

Abstract

Ashy dermatosis is a rare condition, of unknown aetiology, in which mucous membranes are typically spared. The authors report the case of a 57-year-old female with a history of asymptomatic gray-bluish macules located on the trunk and oral mucosa. There were no relief changes on examination. Skin biopsies from the oral mucosa and trunk were performed and both were compatible with ashy dermatosis. The patient started treatment with oral clofazimine but due to the absence of clinical improvement the drug was discontinued three months later. This case report illustrates an atypical case of ashy dermatosis owing to the involvement of mucous membranes, which is rarely described in the literature.

Pediatric ashy dermatosis: what to expect?

“…Palms and soles are usually unaffected 4,5 . Although it usually spares the mucous membranes, lesions on the oral cavity have been reported 6 . In most cases this is an asymptomatic condition but some patients may refer mild pruritus 4 .…”

Erythema Dyschromicum Perstans in an 8-Year-Old Indian Child

“…Typically, erythema dyschromicum perstans presents as ashy gray to grayish brown oval macules/patches symmetrically distributed over the body [ 4 – 7 ]. Sites of predilection include the trunk, followed by the proximal extremities, neck, and face [ 8 ]. The mucosal surfaces, genitals, scalp, palms, soles, and nails are generally spared [ 9 ].…”

“…In adults, the disorder is more prevalent in the Latin American and Asian population [ 1 , 7 , 9 ]. Dark-skinned individuals (Fitzpatrick types IV and V) are most commonly affected [ 1 , 8 , 9 ]. In contrast to the adult population, children with this disorder are usually Caucasians [ 6 , 13 , 14 ].…”

Ashy dermatosis: a review

“…Lesions typically spare the palms, soles, nails, and mucous membranes. However, reports exist of lesions occurring in the oral mucosa [13]. It is typically asymptomatic.…”