Asian and Siberian ginseng as a potential modulator of immune function: an in vitro cytokine study using mouse macrophages

Ginseng, the 'Immunity Boost': The Effects of Panax ginseng on Immune System

“…Treatment of macrophages with RGAPs and IFN-γ significantly increased the production of IL-1β and TNF-α as well as NO as previously described [18]. IL- 12 release was also boosted up by treatment of murine J774A.1 macrophage cells with ginseng extract and its isolated components [20].…”

Ginsenoside Rg1 enhances CD4+ T-cell activities and modulates Th1/Th2 differentiation

“…Recently, Wang et al [29] reported that P. (Asian) ginseng increases production of IL-12 from purified macrophages. This finding contradicts our results because it indicates P. ginseng associates with the Th-1 immune response.…”

Recovery Role of Genistein in Modulating the Alterations in Some Haematological Parameters and Hepatic Antioxidant Enzymes in Gamma Irradiated Mice

“…In addition, it markedly inhibited LP and markedly opposed radical processes and thus reduced the radiation-damage (Kumar et al, 2003). In mouse models, it enhanced the activity of macrophages and caused immune modulation (Wang et al, 2003) and provided protection against acute radiation injury (Landauer et al, 2003). In farm animals, genistein had adjuvant effects in stimulating antibody response (Hu et al, 2003).…”