Asian dust storm events are associated with an acute increase in stroke hospitalisation

Kang, Jiunn Horng; Liu, Tsai Ching; Keller, Joseph J.; Lin, Herng Ching

doi:10.1136/jech-2011-200794

Cited by 51 publications

(21 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…29 The occurrence of Asian dust storms in Korea during early spring is a possible explanation for the increased occurrence of cardioembolic stroke during winter and spring in the present study. 30 Moreover, we observed that the incidence of cardioembolism was highest among ischemic stroke patients living in areas defined as cities, where air pollution is the highest.…”

Section: Strokementioning

confidence: 81%

Air Pollution Is Associated With Ischemic Stroke via Cardiogenic Embolism

Chung

Bang

Ahn

et al. 2017

Stroke

View full text Add to dashboard Cite

Background and Purpose-The aim of the study was to assessed the impact of short-term exposure to air pollution on ischemic stroke subtype, while focusing on stroke caused via cardioembolism. Methods-From a nationwide, multicenter, prospective, stroke registry database, 13 535 patients with acute ischemic stroke hospitalized to 12 participating centers were enrolled in this study. Data on the hourly concentrations of particulate matter <10 μm, nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ), ozone (O 3 ), and carbon monoxide (CO) were collected from 181 nationwide air pollution surveillance stations. The average values of these air pollutants over the 7 days before stroke onset from nearest air quality monitoring station in each patient were used to determine association with stroke subtype. The primary outcome was stroke subtype, including large artery atherosclerosis, small-vessel occlusion, cardioembolism, and stroke of other or undetermined cause. Results-Particulate matter <10 μm and SO 2 concentrations were independently associated with an increased risk of cardioembolic stroke, as compared with large artery atherosclerosis and noncardioembolic stroke. In stratified analyses, the proportion of cases of cardioembolic stroke was positively correlated with the particulate matter <10 μm, NO 2 , and SO 2 quintiles. Moreover, seasonal and geographic factors were related to an increased proportion of cardioembolic stroke, which may be attributed to the high levels of air pollution. Conclusions-Our findings suggest that the short-term exposure to air pollutants is associated with cardioembolic stroke, and greater care should be taken for those susceptible to cerebral embolism during peak pollution periods.

show abstract

Section: Strokementioning

confidence: 81%

Air Pollution Is Associated With Ischemic Stroke via Cardiogenic Embolism

Chung

Bang

Ahn

et al. 2017

Stroke

View full text Add to dashboard Cite

show abstract

“…In Taiwan, a statistically significant association between dust storm events and daily primary intracerebral hemorrhagic stroke admissions, and a positive but non-significant association between dust events and ischemic stroke admission three days after the event, were indicated by Yang et al [163]. Kang et al [164] found a significantly higher number of ischemic stroke admissions two days post-dust event but no difference in hemorrhagic stroke admissions. Kamouchi et al [165] also indicated that Asian dust was not significantly associated with the overall incidence of ischemic stroke, but there was a relationship specific to the stroke subtypes such as atherothrombotic brain infarction in Japan.…”

Section: Desert Dust and Cardiovascular Diseasesmentioning

confidence: 97%

A Systematic Review of Global Desert Dust and Associated Human Health Effects

et al. 2016

View full text Add to dashboard Cite

Dust storms and sandy dust events originating in arid and semi-arid areas can transport particulate material, pollutants, and potential transport long distances from their sources. Exposure to desert dust particles is generally acknowledged to endanger human health. However, most studies have examined anthropogenic particulate sources, with few studies considering contributions from natural desert dust. A systematic literature review was undertaken using the ISI Web of Knowledge and PubMed databases with the objective of identifying all studies presenting results on the potential health impact from desert dust particles across the world. This review reveals an imbalance between the areas most exposed to dust and the areas most studied in terms of health effects. Among the human health effects of dust storms are mortality and morbidity, arising from respiratory system, circulatory system, and other diseases. We summarize the quantitative results of current scientific health research and possible pathological mechanisms, and describe some of the many challenges related to understanding health effects from exposures to desert dust particles. Overall, for respiratory and circulatory mortality, both positive and negative associations have been reported for PM 10 of desert dust, but only a positive relationship was reported between PM 2.5-10 and mortality, and a positive relationship was also reported between PM 2.5 and human mortality. Future pathological studies should continue to focus on those mechanisms causing the most harmful effect of desert dust on respiratory and cardiovascular diseases. More attention should also be paid to the association between desert dust and the morbidity of other diseases, such as those affecting the reproductive system and nervous system.

show abstract

“…[82] Storms are associated with increased risk of stroke hospital admissions that persists for two days following dust storms. [83] Asian studies must adjust their analysis for the confounding effect of Asian dust. Accounting for this adjustment, hemorrhagic and ischemic stroke mortality in Japan between the years of 2005 and 2010 were still increased due to same-day spikes in suspended particulate matter.…”

Section: Air Pollution and Strokementioning

confidence: 99%

Clinical effects of air pollution on the central nervous system; a review

Babadjouni

Hodis

Radwanski

et al. 2017

Journal of Clinical Neuroscience

147

View full text Add to dashboard Cite

The purpose of this review is to describe recent clinical and epidemiological studies examining the adverse effects of urban air pollution on the central nervous system (CNS). Air pollution and particulate matter (PM) are associated with neuroinflammation and reactive oxygen species (ROS). These processes affect multiple CNS pathways. The conceptual framework of this review focuses on adverse effects of air pollution with respect to neurocognition, white matter disease, stroke, and carotid artery disease. Both children and older individuals exposed to air pollution exhibit signs of cognitive dysfunction. However, evidence on middle-aged cohorts is lacking. White matter injury secondary to air pollution exposure is a putative mechanism for neurocognitive decline. Air pollution is associated with exacerbations of neurodegenerative conditions such as Alzheimer’s and Parkinson’s Diseases. Increases in stroke incidences and mortalities are seen in the setting of air pollution exposure and CNS pathology is robust. Large populations living in highly polluted environments are at risk. This review aims to outline current knowledge of air pollution exposure effects on neurological health.

show abstract

Asian dust storm events are associated with an acute increase in stroke hospitalisation

Abstract: The authors conclude that ADS events are associated with an acute increase in stroke admission rates.

Cited by 51 publications

References 65 publications

Air Pollution Is Associated With Ischemic Stroke via Cardiogenic Embolism

Air Pollution Is Associated With Ischemic Stroke via Cardiogenic Embolism

A Systematic Review of Global Desert Dust and Associated Human Health Effects

Clinical effects of air pollution on the central nervous system; a review

Contact Info

Product

Resources

About