Asistencia ventricular externa como soporte circulatorio en un paciente con miocardiopatía dilatada

Objectives To describe the use of ventricular assist devices (VAD) in children in Spain and to identify variables related to survival. Methods This is an observational cohort study of all children younger than 18 years of age who underwent an initial implantation of a VAD at any of the six paediatric heart transplant centers from May 2006 to December 2020. Subjects were identified retrospectively from each hospital's database. Results Paracorporeal VADs were implanted in 118 children (pulsatile [63%], continuous [30.5%] or both types [5.9%]). Small children (< 0.7 m2 of body surface area) comprised the majority of this cohort (63.3%). Overall, 67% survived to VAD explantation, and 64.9% survived to hospital discharge. Non-central nervous system haemorrhage (39%) and stroke (38.1%) were the most common complications. Body weight <5 Kg, congenital heart disease, pre-implantation bilirubin > 34 μmol/L and bridge to decision strategy, were associated with a higher mortality at hospital discharge and in the long-term. Interagency registry for mechanically assisted circulatory support (INTERMACS) status 1 and cardiac arrest prior to VAD implantation were related to long-term mortality, whereas pre-implantation renal replacement therapy and extracorporeal membrane oxygenation were not related to mortality. Conclusions In Spain, 67% of the VAD-supported children have been bridged to heart transplantation or to recovery. Body weight lower than 5 Kg, congenital heart disease diagnosis, cholestatic liver dysfunction, bridge to decision as VAD strategy, INTERMACS-1 status and cardiac arrest were pre-implantation variables related to mortality, whereas pre-implantation renal replacement therapy and extracorporeal membrane oxygenation were not.

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Short- and long-term survival of children treated with ventricular assist devices in Spain, based on 15 years’ experience

Menéndez

Sánchez-Galindo

Balcells

et al. 2023

European Journal of Cardio-Thoracic Surgery

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Asistencia ventricular externa como soporte circulatorio en un paciente con miocardiopatía dilatada

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Short- and long-term survival of children treated with ventricular assist devices in Spain, based on 15 years’ experience

Short- and long-term survival of children treated with ventricular assist devices in Spain, based on 15 years’ experience

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