Asparagus Polysaccharide and Gum with Hepatic Artery Embolization Induces Tumor Growth and Inhibits Angiogenesis in an Orthotopic Hepatocellular Carcinoma Model

Weng, Lingling; Xiang, Jianfeng; Lin, Jinbo; Yi, Shanghui; Yang, Lei; Li, Yi-Sheng; Zeng, Hao-Tao; Lin, Shengming; Xin, Dongwei; Zhao, Hailiang; Qiu, Shuqi; Chen, Tao; Zhang, Minguang

doi:10.7314/apjcp.2014.15.24.10949

Cited by 13 publications

(11 citation statements)

References 29 publications

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“…In addition, asparagus polysaccharide was a good embolic candidate in transcatheter arterial chemoembolization (TACE), a minimally invasive treatment for unresectable HCC. The combined treatment of asparagus polysaccharide with TACE markedly suppressed liver tumor growth as well as prolonged survival time in rat model with little toxicity [ 63 ].…”

Section: Vegetablesmentioning

confidence: 99%

Dietary Natural Products for Prevention and Treatment of Liver Cancer

et al. 2016

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Liver cancer is the most common malignancy of the digestive system with high death rate. Accumulating evidences suggests that many dietary natural products are potential sources for prevention and treatment of liver cancer, such as grapes, black currant, plum, pomegranate, cruciferous vegetables, French beans, tomatoes, asparagus, garlic, turmeric, ginger, soy, rice bran, and some edible macro-fungi. These dietary natural products and their active components could affect the development and progression of liver cancer in various ways, such as inhibiting tumor cell growth and metastasis, protecting against liver carcinogens, immunomodulating and enhancing effects of chemotherapeutic drugs. This review summarizes the potential prevention and treatment activities of dietary natural products and their major bioactive constituents on liver cancer, and discusses possible mechanisms of action.

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Section: Vegetablesmentioning

confidence: 99%

Dietary Natural Products for Prevention and Treatment of Liver Cancer

et al. 2016

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“…The results showed a certain tumor inhibitory effect of them via promoting cell apoptosis and suppressing tumor angiogenesis when given as transarterial chemoembolization (TACE) therapy. Meanwhile, it exerted the antihepatoma activity with lower toxic effects as well as reduced kidney and liver functional damage, highlighting its chemotherapeutic potential in clinical application for future liver cancer TACE therapy [51].…”

Section: Functional Roles Of Chinese Medicine Extracts and Fractions mentioning

confidence: 99%

What Chinese Medicine Can Do for Liver Cancer?

Chen¹,

Wang²,

Feng³

2018

Liver Cancer

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Liver cancer is an international problem, especially in Asian countries. It is because that most liver cancers are already late stage when they are diagnosed, and also most liver cancers have various previous chronic liver diseases induced by alcoholic, virus, and steatosis, etc. In recent years, laboratory and clinical studies focusing on liver cancer by Chinese medicine has been extensively studied. What Chinese medicine treatment formalities can be used in liver cancer? How Chinese medicine can be employed in treatment of liver cancer? What Chinese medicine can contribute to liver cancer? To answer these questions in this chapter, we will review and discuss treatment of liver cancer from Chinese medicine's perspective with scientific evidences as following three parts: (1) Chinese medicine as the source of discovering new treatment for liver cancer, (2) Chinese medicine as a complementary treatment of liver cancer, and (3) to discuss future research and application of Chinese medicine in liver cancer treatment.

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“…TCM can also alleviate the adverse reaction of combined chemotherapeutic agents and promote the recovery of liver function in patients [74,75]. Secondly, TCM can significantly inhibit liver tumor growth and angiogenesis [76,77], while restraining the progress of liver cancer [78,79]. Thirdly, TCM can promote the immune response and improve the QOL of the patient by protecting life functions [74,80], and then prolong survival of patients and improve the prognosis of patients with unrespectable HCC [70,[81][82][83].…”

Section: Combination Of Tcm and Interventional Therapy For Treatment mentioning

confidence: 99%

Traditional Chinese medicine combined with other therapies for treatment of hepatocellular carcinoma in clinical trials

Feng¹,

Zhu²,

Hu³

et al. 2017

Cancer Rep Rev

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Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide with a high mortality, and still there are only few effective methods to treat it. To this end, alternative medicines from traditional Chinese medicine (TCM) are being investigated for their ability to eliminate the tumor or halt its progression. A large number of studies have shown that TCM can be an effective approach to treat the HCC in clinical trials when used alone or in combination with other therapies. Thus, TCM has made significant progress, and has begun to gain worldwide popularity for promoting healthcare and HCC treatment. Because of this progress, periodic summaries are needed to facilitate further research for the use of TCM to treat HCC. This paper provides a comprehensive summary of this work with regard to the following aspects: herbalist views on the etiology and therapeutic principles for treatment of HCC, treating HCC by TCM alone, treating HCC with TCM in combination with resection, chemotherapy, radiotherapy and interventional therapy, and other therapies. Additionally, the current main problems and future application prospects for treatment of HCC by TCM described, which could provide scientific guidance for clinician as well as references for the treatment of other cancers.

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Asparagus Polysaccharide and Gum with Hepatic Artery Embolization Induces Tumor Growth and Inhibits Angiogenesis in an Orthotopic Hepatocellular Carcinoma Model

Cited by 13 publications

References 29 publications

Dietary Natural Products for Prevention and Treatment of Liver Cancer

Dietary Natural Products for Prevention and Treatment of Liver Cancer

What Chinese Medicine Can Do for Liver Cancer?

Traditional Chinese medicine combined with other therapies for treatment of hepatocellular carcinoma in clinical trials

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