Aspects of Cognition/Health Failure by HIV-infected Individuals: Amelioration through Exercise

Archer, Trevor

doi:10.4172/2572-0805.1000e101

Cited by 4 publications

(3 citation statements)

References 21 publications

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“…The problem in sub-Saharan area is expected to be large as HIV infection and its sequel are prevalent in the region (2,4). Previous studies conclude that neurocognitive deficit has been found at any stage of the illness (5,6,7,8). …”

Section: Introductionmentioning

confidence: 99%

Prevalence of HIV associated neurocognitive deficit among HIV positive people in Ethiopia: a cross sectional study at Ayder Referral Hospital

Belete¹,

Medfu²,

Yemiyamrew³

2017

Ethiop J Health Sci

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BACKGROUND: HIV associated neurocognitive deficit impairs motor activity, neuropsychiatric functioning, daily activity and work activity usually due to the immune suppression effect of the virus. Sub-Saharan region including Ethiopia is the region with the highest burden of HIV. However, a few studies are found on this aspect nationally. This study was aimed at determining the prevalence and the factors associated with cognitive impairment among HIV positive people in Ethiopia who attended Ayder Comprehensive Specialized Hospital. METHOD: A hospital based cross sectional study was employed on 234 participants selected using systematic random sampling technique. Data was collected thrpugh face-to-face interview, observation and document review. International HIV dementia scale, activity of daily living scale and Hospital Anxiety and Depression scale were used to assess neuro cognitive deficit, activity of daily living, anxiety and depression respectively. The data was analyzed by using SPSS window 20. RESULT: About 88% of the subjects were receiving highly active antiretroviral therapy. The magnitude of Neuro cognitive deficit was 33.3% (95% CI; 27.7% -40.6%). Impairment in the activity of daily living was observed on 9.8% of the participants. Besides, 55.6% and 67.1% had anxiety and depressive disorders respectively. Late clinical stage of the illness (AOR= 4.2 (95% CI; 1.19, 14.44)) and impairment in the activity of daily living were significantly associated with neurocognitive deficit (AOR= 7.19 (95% CI; 1.73, 21.83). CONCLUSION: A higher prevalence of neurocognitive deficit was observed that was related to impaired activity of daily living and being in late stages of the illness. Hence, this should be a strong alarm for early detection of the problem and consistent review of the treatment regimen.

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Section: Introductionmentioning

confidence: 99%

Prevalence of HIV associated neurocognitive deficit among HIV positive people in Ethiopia: a cross sectional study at Ayder Referral Hospital

Belete¹,

Medfu²,

Yemiyamrew³

2017

Ethiop J Health Sci

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“…Progressive behavioral and neurological dysfunctions are associated with human immunodeficiency virus type 1 (HIV-1) that involve impairments within several areas of neurocognitive expression [1][2][3], brain integrity [4][5][6][7] and motor and everyday behavioral functioning [8,9]. Due to these functional and cerebral dysregulations the availability of possible therapeutics is easily reconciled with existing demand [10]. Regular physical exercise offers protection against adverse inflammatory, neurobehavioral, epigenetic and metabolic outcomes of trauma with the promise of disease prevention [11][12][13][14].…”

Section: Editorialmentioning

confidence: 99%

Physical Exercise Improves Health Domains in HIV Patients: ’Lifting a Burden’

Archer¹

2016

HIV Curr Res

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“…Because of the risk of transmission, major and permanent changes are called for in sexual behavior and risk bearing life styles which may not be easily modifiable. However, while treatment success maintains its primary positions in such evaluations, researchers have been making efforts to assess the degree to which chronic clinical disorders and their treatments affect patient's functional capacity, overall sense of well-being, psychological and social health [40][41][42][43][44][45][46]. Quality of life assessment measures changes in physical, functional, mental and social health in order to evaluate the human and financial costs and benefit of new programmers and interventions [47][48][49][50].…”

Section: Introductionmentioning

confidence: 99%

Correlation of Socio-Demographic and Clinical Factors with Quality of Life (QOL) Among Subjects Living with HIV in Port Harcourt, Nigeria

2019

AIDT

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Background: HIV, a viral infectious disease, predominantly affects the physical, social and psychological well-being of PLWHIV which further affect their quality of life. A number of socio-demographic and clinical factors may play important roles. Aim: The aim of this study, therefore, was to determine the relationship between some socio-demographic and clinical factors and quality of life among PLWHIV. Methodology: Following ethical approval from the appropriate committee of the hospital and informed consent from the participants, 230 subjects (PLWHIV), were recruited through a systematic random sampling method based on the study’s inclusion and exclusion criteria. Subjects were administered with the study’s instruments including the socio-demographic questionnaire, the brief version of the WHO Quality of Life instrument (WHOQOL-Bref). The data were analyzed using the SPSS version 20 statistical package. Confidence interval was set at 95% while P- value of less than 0.05 was considered statistically significant. Results: The study found PLWHIV domain scores quality of life as follows; 60.71±15.57, 62.34±26.32, 61.57±25.04, 55.15±14.00 and 65.81±21.84 for physical, psychological, social relationship, environment domains and general health facet respectively. Age group below 20 years, tertiary education, married with high to average monthly income, no stigmatization, with less emotional reaction were associated with the best quality of life. The only significant relationships were that(i) those who indicated no feelings of stigma had significantly higher quality of life than those who admitted having stigma in the physical domain(p=0.017); (ii) those who were widowed or divorce had significantly lower quality of life than all the other marital groups in the social domain(p=0.002). Conclusion: The findings in this study indicate some socio0demorgraphic and clinical factors may play significant role in the degree to which HIV infection affects quality of life of the sufferers. It is therefore important that the management of HIV should include attention to factors in order to enhance the quality of care and hence their quality of life.

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Aspects of Cognition/Health Failure by HIV-infected Individuals: Amelioration through Exercise

Cited by 4 publications

References 21 publications

Prevalence of HIV associated neurocognitive deficit among HIV positive people in Ethiopia: a cross sectional study at Ayder Referral Hospital

Prevalence of HIV associated neurocognitive deficit among HIV positive people in Ethiopia: a cross sectional study at Ayder Referral Hospital

Physical Exercise Improves Health Domains in HIV Patients: ’Lifting a Burden’

Correlation of Socio-Demographic and Clinical Factors with Quality of Life (QOL) Among Subjects Living with HIV in Port Harcourt, Nigeria

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