The aim of this entry is to discuss the main notions characterizing the academia of the twenty-first century, examining the sphere of online learning. To investigate the mentioned relations and complexities within academic learning itself, the 5S Model of Online Academia has been created and discussed by this author. This model focuses the discussion about online academia on such elements as subject, situation, spirit, stakeholder, senses and subject, and their subcategories, to elaborate on the multilevel nature of universities. This framework provides an insight into the current complexities of online academia and offers an insight into its future perspectives.