2016
DOI: 10.4103/0253-7184.188482
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Aspergillus meningoencephalitis in a patient with human immunodeficiency virus infection: Normal cerebrospinal fluid does not mean absence of meningitis

Abstract: A male with human immunodeficiency virus infection presented with febrile encephalopathy followed by seizures and left hemiparesis. Initial imaging with contrast computerized tomography (CT) scan brain and cerebrospinal fluid (CSF) examination were normal. Subsequent magnetic resonance imaging brain revealed bilateral parieto-occipital infarcts with bleed. He did not improve on treatment with broad-spectrum antibiotics, anti-tubercular drugs, and antifungals. He finally succumbed to the disease. His CSF cultur… Show more

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Cited by 4 publications
(2 citation statements)
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“…S. pneumoniae, N. meningitidis and Aspergillus spp. are of particular concern in the HSCT population [27,[42][43][44][45].…”
Section: Host Factorsmentioning
confidence: 99%
See 1 more Smart Citation
“…S. pneumoniae, N. meningitidis and Aspergillus spp. are of particular concern in the HSCT population [27,[42][43][44][45].…”
Section: Host Factorsmentioning
confidence: 99%
“…In a study by Antinori, et al, only 56% of patients were diagnosed prior to death [13]. CSF fungal culture is only 31% sensitive among all hosts, and 18% in immunocompromised hosts [13,43,44,168,169]. Multiple, large volume CSF cultures may improve sensitivity [13,167].…”
Section: Aspergillus Meningitismentioning
confidence: 99%