2022
DOI: 10.4103/jcvjs.jcvjs_35_22
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Aspergillus spinal epidural abscess

Abstract: Aspergillus spinal epidural abscess (ASEA) is a rare entity that may mimic Pott's paraplegia as it commonly affects immunocompromised patients. We present one institutional case of ASEA with concomitant review of the literature. A 58-year-old female presented with intermittent low back pain for 10 years recently aggravated and with concurrent spastic paraparesis, fever, and weight loss. Emergent magnetic resonance imaging (MRI) showed T11–T12 epidural abscess with discitis and osteomyelitis. After empirical tr… Show more

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Cited by 7 publications
(8 citation statements)
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References 24 publications
(14 reference statements)
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“…Prompt diagnosis and treatment of SEA is essential as delay can result in paralysis or death. 1 6 17 22 23 24 Due to its low incidence and nonspecific presentation, accurately diagnosing SEA can be challenging with up to 75% of cases being misdiagnosed, misdiagnosis is alarmingly common. 1 18 23 25 26 There is a significant reduction in diagnostic delays by implementing a novel decision guideline using risk factor assessment followed by ESR and CRP testing before obtaining definitive imaging for suspected SEA.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Prompt diagnosis and treatment of SEA is essential as delay can result in paralysis or death. 1 6 17 22 23 24 Due to its low incidence and nonspecific presentation, accurately diagnosing SEA can be challenging with up to 75% of cases being misdiagnosed, misdiagnosis is alarmingly common. 1 18 23 25 26 There is a significant reduction in diagnostic delays by implementing a novel decision guideline using risk factor assessment followed by ESR and CRP testing before obtaining definitive imaging for suspected SEA.…”
Section: Discussionmentioning
confidence: 99%
“…notably for cellulitis (39%) [43]. Linked to this condition, several microorganisms can be disseminated via hematogenous or lymphatic routes, perpetuating the proliferation of bacteria in unusual places.…”
Section: Accepted Manuscriptmentioning
confidence: 99%
“…The most typical site for Aspergillus osteomyelitis is vertebral bodies. Also, a few cases of Aspergillus epidural abscess have been documented in the literature 9 …”
Section: Discussionmentioning
confidence: 99%
“…It has a significant mortality rate and is the cause of about one‐third of fatalities 7 . Patients with CGD infrequently develop osteomyelitis or spinal/epidural abscesses caused by Aspergillus species 8,9 . Pneumonia is the most typical type of aspergillosis in patients with CGD and it is frequently associated with spread to soft tissues, chest wall, ribs, or spine 8 …”
Section: Introductionmentioning
confidence: 99%
“…Pharmacological management alone was used in three cases of which only one survived. This opportunistic infection is most commonly seen in immunocompromised patients, including those on corticosteroid therapy [13][14][15]. The typical clinical presentation of ASEA includes nonspecific symptoms such as fever, back pain, weakness, and paresis [15].…”
Section: Discussionmentioning
confidence: 99%