2015
DOI: 10.1055/s-0035-1554389
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Aspergillus Spondylodiscitis in Immunocompetent Patients: A Report of Two Cases

Abstract: Introduction The term spondylodiscitis refers to infection of the disc space and adjacent vertebrae. It is commonly caused by Mycobacterium tuberculosis and bacterial pathogens; whereas fungal spondylodiscitis is extremely rare in immunocompetent individuals.1 The reported incidence of fungal spondylodiscitis in studies is 0.5 to 1.6%.2 Aspergillus species (normal inhabitants of the respiratory tract) are commonly responsible for fungal spondylodiscitis. They invade the spine in immunocompromised hosts, such a… Show more

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“…Aspergillus is a saprophytic fungus that lives mostly in soil and plants. The incidence of Aspergillus affecting the bone among all cases of invasive aspergillosis is estimated to be 3%.They infiltrate the spine in immunocompromised patients, such as those who have had an organ transplant, are on chronic steroid medication, or are undergoing chemotherapy [1]. Invasive aspergillosis can migrate from the lungs to the brain, kidneys, heart, and bones, with the spine being a main target.…”
Section: Introductionmentioning
confidence: 99%
“…Aspergillus is a saprophytic fungus that lives mostly in soil and plants. The incidence of Aspergillus affecting the bone among all cases of invasive aspergillosis is estimated to be 3%.They infiltrate the spine in immunocompromised patients, such as those who have had an organ transplant, are on chronic steroid medication, or are undergoing chemotherapy [1]. Invasive aspergillosis can migrate from the lungs to the brain, kidneys, heart, and bones, with the spine being a main target.…”
Section: Introductionmentioning
confidence: 99%