Aspiration Thrombectomy in a Case of Acute Myocardial Infarction Due to Coronary Emboli in a Patient with Peripartum Cardiomyopathy and Mural Thrombus

Abdulbaki, Abdulrahman; Kocherla, Cyrus; Modi, Kalgi

doi:10.5301/heartint.5000225

Cited by 5 publications

(4 citation statements)

References 10 publications

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“…15 Although most of them are central, pulmonary and peripheral, coronary thromboembolism has been reported in only 4 cases and is one of the most risky and challenging in differential diagnosis among all thromboembolic complications. [8][9][10][11] No clinical studies are available to guide treatment for cases of coronary embolism without underlying coronary disease, but initiation of reperfusion therapy is indicated (standard for myocardial infarction). Unlike the previous 4 cases, in our case, the thrombus material was embolized to the RCA, not to the left coronary arteries (Figure 4).…”

Section: Discussionmentioning

confidence: 99%

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A Rare Case of Peripartum Cardiomyopathy Followed Up for Intracardiac Thrombus and Sudden Embolism of Right Coronary Artery: A Case Report and Review of the Literature

Toprak¹,

BİÇER²,

Taşçanov³

et al. 2023

J Clin Obstet Gynecol

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ABS TRACT Peripartum cardiomyopathy (PPCM) is a rare disease with high mortality in which dilated heart failure occurs in the last month of pregnancy or within 5 months after delivery, without any other etiology or pre-existing heart disease. Sometimes, it may present with intracardiac thrombus and associated life-threatening embolic complications. Here, we will present the management of a 28-year-old patient who was diagnosed with PPCM and intracardiac thrombus immediately after delivery and was followed up in the intensive care unit, in which an inferior myocardial infarction was detected in the electrocardiogram taken for sudden onset chest pain. Although peripheral thromboembolism is occasionally detected in PPCM patients with intracardiac thrombus, coronary embolisms is not common. Presentation with coronary embolism in patients with PPCM has been described in only 4 cases in the literature, but to the best of our knowledge, this is the first case to describe embolism to the right coronary artery.

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Section: Discussionmentioning

confidence: 99%

“…4 Although central, peripheral, and pulmonary thromboembolism cases have been described in the literature, only 4 cases of coronary embolism have been described, and to the best of our knowledge, this is the first case presenting with inferior myocardial infarction as a result of thromboembolization to the right coronary artery (RCA). [5][6][7][8][9][10][11]…”

mentioning

confidence: 99%

A Rare Case of Peripartum Cardiomyopathy Followed Up for Intracardiac Thrombus and Sudden Embolism of Right Coronary Artery: A Case Report and Review of the Literature

Toprak¹,

BİÇER²,

Taşçanov³

et al. 2023

J Clin Obstet Gynecol

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“… 21 Thrombosis may occur in both the right and left ventricle. 89–91 Another noteworthy complication of peripartum cardiomyopathy is cardiogenic shock found in 2.6% of women in the United States between 2004 and 2011. In the face of these complications, mechanical circulatory support was used in 1.5% of cases and heart transplantation was performed in only 0.5% of women.…”

Section: Methodsmentioning

confidence: 99%

The Relationship Between Peripartum Cardiomyopathy and Preeclampsia – Pathogenesis, Diagnosis and Management

Kuć¹,

Kubik-Machura²,

Kościelecka³

et al. 2022

JMDH

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Peripartum cardiomyopathy (PPCM) is a condition with an incompletely understood etiology, although many risk factors for this disorder have been mentioned. Preeclampsia (PE) is a rare but undoubtedly very important cause of PPCM. Early recognition and prompt treatment of preeclampsia and peripartum cardiomyopathy are essential to optimize pregnancy outcomes. An extensive manual search of major electronic databases was conducted in November 2021. The following literature review provides a comprehensive discussion of peripartum cardiomyopathy and preeclampsia and quantifies the prevalence of PE in women with PPCM. The authors highlighted aspects such as epidemiology, risk factors, cardiovascular changes, diagnosis and clinical presentation, and management and complications. Accumulating data indicate that both conditions have a similar pathogenesis characterized by vascular abnormalities. In both conditions we can observe an increase in interleukin-6 and gamma interferon, CCL2/MCP1, and decreased SOD activity. sFLT1 (a soluble form of fms-like tyrosine kinase 1), a substance with antiangiogenic and probably cardiotoxic effects, may be important. Preeclampsia and peripartum cardiomyopathy are characterized by recurrence rates that follow a similar pattern in subsequent pregnancies, and mortality remains a concern. Our analysis highlights the need to better understand the co-morbidity of PE and PPCM, and the need to qualify patients for the same clinical trials because of the common origin of these conditions.

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“…Thrombosis may occur in both left sided and right sided cardiac chambers 7374101102103104105106107108. Mechanisms underlying intracardiac thrombosis in PPCM include cardiac dilatation and hypocontractability leading to blood stasis, as well as endothelial injury 13.…”

Section: Natural Course and Prognosismentioning

confidence: 99%

Peripartum cardiomyopathy

Honigberg

Givertz

2019

BMJ

145

154

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Peripartum cardiomyopathy (PPCM) is a rare, often dilated, cardiomyopathy with systolic dysfunction that presents in late pregnancy or, more commonly, the early postpartum period. Although the condition is prevalent worldwide, women with black ancestry seem to be at greatest risk, and the condition has a particularly high incidence in Nigeria and Haiti. Other risk factors include pre-eclampsia, advanced maternal age, and multiple gestation pregnancy. Although the complete pathophysiology of peripartum cardiomyopathy remains unclear, research over the past decade suggests the importance of vasculo-hormonal pathways in women with underlying susceptibility. At least some women with the condition harbor an underlying sarcomere gene mutation. More than half of affected women recover systolic function, although some are left with a chronic cardiomyopathy, and a minority requires mechanical support or cardiac transplantation (or both). Other potential complications include thromboembolism and arrhythmia. Currently, management entails standard treatments for heart failure with reduced ejection fraction, with attention to minimizing potential adverse effects on the fetus in women who are still pregnant. Bromocriptine is one potential disease specific treatment under investigation. In this review, we summarize the current literature on peripartum cardiomyopathy, as well as gaps in the understanding of this condition and future research directions.

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Aspiration Thrombectomy in a Case of Acute Myocardial Infarction Due to Coronary Emboli in a Patient with Peripartum Cardiomyopathy and Mural Thrombus

Cited by 5 publications

References 10 publications

A Rare Case of Peripartum Cardiomyopathy Followed Up for Intracardiac Thrombus and Sudden Embolism of Right Coronary Artery: A Case Report and Review of the Literature

A Rare Case of Peripartum Cardiomyopathy Followed Up for Intracardiac Thrombus and Sudden Embolism of Right Coronary Artery: A Case Report and Review of the Literature

The Relationship Between Peripartum Cardiomyopathy and Preeclampsia – Pathogenesis, Diagnosis and Management

Peripartum cardiomyopathy

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