Assembly of Phospha‐Xanthenes from Functionalized Organophosphines and Arynes through a Formal (4+2) Annulation‐Inspired Cascade

Abstract

Herein, we report an approach to phospha‐xanthenes from <i>ortho</i>‐chalcone based organophosphines and arynes. These reactions proceeded through a sequential process consisting of a formal [4+2] cycloaddition, arylation, P‐OH formation and P‐C bond cleavage. A gram‐scale preparation and a chemical conversion were performed to demonstrate the synthetic utility of this method. Also, a possible mechanism was proposed based on the control experiments.