This research aims to evaluate whether agritourism is a sustainable activity, comparing the profiles of accommodation, farmers, and accommodation with agricultural activities. Four specific objectives drive this study: (a) examining the cultural/landscape, economic, environmental, and social indicators of sustainability; (b) comparing indicators of sustainability between groups; (c) revealing whether there is a significant cross-correlation between spatial distribution and its impact on sustainability metrics; (d) discussing the significance of these factors for tourism development policies. The present study uses various techniques to study the degree of equilibrium in the distribution of the accommodation and farms in relation to their sustainable impact. To verify this, we use the global Moran’s I and G (d) tests proposed by Getis and Ord. As well as analyzing local contrasts, LISA (Local Indicators of Spatial Association) and Hot Spot analysis are used for mapping. The main results reveal different profiles of sustainability, highlighting the accommodation profile with the lowest contribution to sustainable development, while profiles where the relationship between agriculture and tourism is most visible seem to perform better. In general, the main results obtained suggest that there is no direct relationship between spatial distribution and sustainability inputs, excluding the potential of endogenous resources, and suggesting the existence of imbalances in the creation of agritourism products.