Assessing an Intervention to Improve Clinical Trial Perceptions Among Predominately African-American Communities in South Carolina

Ford, Marvella E.; Wahlquist, Amy E.; Blake, Rashell; Green, CoDanielle; Streets, June; Fuller, Ebonie; Johnson, Erica R.; Jefferson, Melanie; Etheredge, James; Varner, Heidi; Johnson, Stewart P.; Glover, Saundra H.; Turner, David; Garrett‐Mayer, Elizabeth

doi:10.1353/cpr.2012.0038

Cited by 19 publications

(17 citation statements)

References 26 publications

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“…Other projects (Langford et al, 2010; Wallington et al, 2012) are difficult to compare because they use a single item to measure awareness of clinical trials. While some recent research (Ma et al, 2014; Quinn et al, 2013) with general community members did not examine attitudes toward CCTs, M. E. Ford et al (2012) found that a 7-item measure of attitudes improved among African Americans with poor baseline perceptions after a 30-minute segment of a 3.5-hour cancer education program.…”

Section: Discussionmentioning

confidence: 93%

Adaptation of a Cancer Clinical Trials Education Program for African American and Latina/o Community Members

et al. 2015

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The pilot study reported in this article culturally and linguistically adapted an educational intervention to promote cancer clinical trials (CCTs) participation among Latinas/os and African Americans. The single-session slide presentation with embedded videos, originally developed through a campus–community partnership in Southern California, was chosen for adaptation because it was perceived to fit the CORRECT model of innovation (credible, observable, relevant, relatively advantageous, easy to understand, compatible, and testable) and because of the potential to customize any components not identified as core, allowing them to be revised for cultural and linguistic alignment in New York City. Most of the 143 community participants (76.2%) were female; most (54.6%) were older than 59 years. More than half (78.3%) preferred to speak English or were bilingual in English and Spanish. A large proportion (41.3%) had not completed high school. Knowledge and perceived benefits and barriers regarding CCT showed small, though statistically significant, increases. There were no statistically significant group differences for changes in mean knowledge, perceived benefits, or perceived barriers when examined by ethnicity, education level, language, or other included sociodemographic variables. However, a small, but statistically significant difference in perceived barriers was observed when examined by country of origin, with the foreign born score worsening 0.08 points (SD = 0.47, p = .007) on the 5-point Likert-type scale administered posteducation compared to preeducation. Participants’ open-ended comments demonstrated the acceptability of the topic and intervention. This adaptation resulted in an intervention with the potential to educate African American and Latina/o general community members in a new geographic region about the purpose, methods, and benefits of CCTs.

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Section: Discussionmentioning

confidence: 93%

Adaptation of a Cancer Clinical Trials Education Program for African American and Latina/o Community Members

et al. 2015

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“…While other interventions have included a focus on community-based cancer clinical trials education, the evidence in the literature is limited regarding effective approaches to cultural adaptation of cancer clinical trials education [17, 23–25]. ENACCT’s use of Learning and Feedback sessions in the Community Bridges project is an innovative, collaborative method for culturally adapting cancer clinical trials education messaging, resulting in the development of multiple, flexible, interactive training formats and greater community ownership of training content.…”

Section: Discussionmentioning

confidence: 99%

“…Reversing this trend requires increasing minority groups’ awareness of clinical trials [8]. Numerous experts have suggested that improving general cancer clinical trial awareness, access, and acceptability as well as addressing distrust may potentially help overcome barriers to [3,8,14–17]. Key education messages in particular should be targeted to address unique interests and concerns African- Americans have regarding research participation.…”

Section: Introductionmentioning

confidence: 99%

Collaborative Development of Clinical Trials Education Programs for African-American Community-Based Organizations

Blakeney¹,

Michaels²,

Green³

et al. 2014

J Canc Educ

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This paper describes the use of a unique ”Learning and Feedback” approach to tailor cancer clinical trials education programs for Community Bridges, a peer training intervention designed for African American communities in North Carolina. Generic community education modules were demonstrated with key community leaders who were designated as trainers. Quantitative and qualitative assessments were provided on understanding of content, comfort with material and cultural relevance. The generic materials were adapted into three revised modules, all featuring key messages about cancer clinical trials, discussion regarding distrust of medical research, common misconceptions about trials, patient protections, and a call to action to prompt increased inquiry about locally available trials. The revised modules were then used as part of a train-the-trainer program with 12 African American community leaders. ENACCT’s use of the Learning and Feedback process is an innovative method for culturally adapting clinical trials education.

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“…Despite their disproportionate burden of cancer, racial and ethnic minorities are less likely to participate in cancer clinical trials (Ford JG, 2008; Ford et al, 2012; Ford ME, 2013; Langford A, 2010; Seifer, Michaels, & Collins, 2010). The underrepresentation of ethnically diverse populations in cancer clinical trials results in the inequitable distribution of the risks and benefits of this research (Hartz et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Applying a Conceptual Framework to Maximize the Participation of Diverse Populations in Cancer Clinical Trials

Nápoles

Cook

Ginossar

et al. 2017

Advances in Cancer Research

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The underrepresentation of ethnically diverse populations in cancer clinical trials results in the inequitable distribution of the risks and benefits of this research. Using a case study approach, we apply a conceptual framework of factors associated with the participation of diverse population groups in cancer clinical trials developed by Dr. Jean Ford and colleagues to increase understanding of the specific strategies, and barriers and promoters addressed by these strategies, that resulted in marked success in accrual of racially and ethnically diverse populations in cancer clinical research. Results indicate that the studies presented were able to successfully engage minority participants due to the creation and implementation of multi-level, multifaceted strategies that included: culturally and linguistically appropriate outreach, education, and research studies that were accessible in local communities; infrastructure to support engagement of key stakeholders, clinicians, and organizations serving minority communities; testimonials by ethnically diverse cancer survivors; availability of medical interpretation services; and providing infrastructure that facilitated the engagement in clinical research of clinicians who care for minority patient populations. These strategic efforts were effective in addressing limited awareness of trials, lack of opportunities to participate, and acceptance of engagement in cancer clinical trials. Careful attention to the context and population characteristics in which cancer clinical trials are conducted will be necessary to address disparities in research participation and cancer outcomes. These studies illustrate that progress on minority accrual into clinical research requires intentional efforts to overcome barriers at all three stages of the accrual process: awareness, opportunity and acceptance of participation.

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Assessing an Intervention to Improve Clinical Trial Perceptions Among Predominately African-American Communities in South Carolina

Cited by 19 publications

References 26 publications

Adaptation of a Cancer Clinical Trials Education Program for African American and Latina/o Community Members

Adaptation of a Cancer Clinical Trials Education Program for African American and Latina/o Community Members

Collaborative Development of Clinical Trials Education Programs for African-American Community-Based Organizations

Applying a Conceptual Framework to Maximize the Participation of Diverse Populations in Cancer Clinical Trials

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