“…Adopting these principles and applying them to PW samples in order to quantify the ecotoxicological impacts that actually arise following exposure, will provide a huge step forward in obtaining a greater understanding of the effects of PW releases on the marine environment. The scientific literature contains a few examples in which the ecotoxicological effects of PAHs and APs in PW on different organisms have been investigated (Beyer et al, 2012;Skadsheim et al, 2009;Brooks et al, 2011;Rastall et al, 2006;Meier et al, 2007;Sundt and Bjorkblom, 2011). Mussels were exposed to 0%, 0.01%, 0.1%, 0.5% and 1% dilutions of PW samples and significant sublethal responses in acyl-CoA oxidase activity, neutral lipid accumulation, catalase activity, micronuclei formation, lysosomal membrane stability in digestive cells and haemocytes, cell-type composition in digestive gland epithelium, and the integrity of the digestive gland tissue were observed (Brooks et al, 2011).…”