Assessing Disparities in the Prevalence of Atopic Comorbidities Among Food-Allergic Children

Health disparities in allergic diseases

“…The prevalence of self-or parent-reported food allergies was highest among those earning <$150 000 per year [27 & ]. ) in food allergies and anaphylaxis among Black participants compared to other races and ethnicities [29]. The SAPPHIRE study found genetic ancestry was not significantly associated with food allergy, suggesting that socioenvironmental factors play a greater role in food allergy disparities, compared to ancestry or ethnicity [28].…”

“…The SAPPHIRE study found genetic ancestry was not significantly associated with food allergy, suggesting that socioenvironmental factors play a greater role in food allergy disparities, compared to ancestry or ethnicity [28]. The FORWARD study also revealed that socioeconomic factors measured through the area deprivation index (ADI), a validated, multicomponent percentile score was independently associated with asthma and allergic rhinitis in children with food allergy [29].…”

“…A small longitudinal cohort study of individuals with and without asthma from Southeast Michigan and the Detroit metropolitan area [The Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE)] [ 28 ] and a prospective, multicenter cohort study investigating the natural history of pediatric atopy: the Food Allergy Outcomes Related to White and African American Racial Differences (FORWARD) study observed that allergy to seafood, especially shrimp, accounted for the largest difference (13.1% vs. 4.6%; P = 1.38 × 10 −31 ) in food allergies and anaphylaxis among Black participants compared to other races and ethnicities [ 29 ]. The SAPPHIRE study found genetic ancestry was not significantly associated with food allergy, suggesting that socioenvironmental factors play a greater role in food allergy disparities, compared to ancestry or ethnicity [ 28 ].…”

“…The SAPPHIRE study found genetic ancestry was not significantly associated with food allergy, suggesting that socioenvironmental factors play a greater role in food allergy disparities, compared to ancestry or ethnicity [ 28 ]. The FORWARD study also revealed that socioeconomic factors measured through the area deprivation index (ADI), a validated, multicomponent percentile score was independently associated with asthma and allergic rhinitis in children with food allergy [ 29 ]. The ADI is a proxy for local socioeconomic conditions, to characterize neighborhoods based on multiple social determinants of health including income, education, employment, and housing quality, with a high ADI associated with a risk of poor health outcomes [ 30 ].…”