2024
DOI: 10.3389/fonc.2024.1306255
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Assessing of case–cohort design: a case study for breast cancer patients in Xinjiang, China

Mengjuan Wu,
Tao Zhang,
Chunjie Gao
et al.

Abstract: ObjectiveTo assess the effectiveness and clinical value of case–cohort design and determine prognostic factors of breast cancer patients in Xinjiang on the basis of case–cohort design.MethodsThe survival data with different sample characteristics were simulated by using Cox proportional risk models. To evaluate the effectiveness for the case–cohort, entire cohort, and simple random sampling design by comparing the mean, coefficient of variation, etc., of covariate parameters. Furthermore, the prognostic factor… Show more

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