Assessing osteoporosis risk factors in Spanish menopausal women

Pérez, José Antônio Martínez; Palacios, Santiago; García, Felipe Chavida; Pérez, Maite

doi:10.3109/09513590.2010.540599

Cited by 15 publications

(5 citation statements)

References 38 publications

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“…4 The mean 10-year absolute fracture risk for major and hip fractures (FRAX® tool) is displayed in the different decades of age fractures in our sample. Similar results concerning family history together with age and early onset of the menopause came from a Spanish study assessing osteoporosis risk factors in menopausal women [24]. In a case-control study of Belgrade women, the following factors were related to osteoporosis: low body weight, previous fractures, early menopause, and family history for fractures [25].…”

Section: Risk Factors For Osteoporosis and 10-year Absolute Fracture supporting

confidence: 68%

Femoral neck bone mineral density and 10-year absolute fracture risk in a national representative sample of Bulgarian women aged 50 years and older

Borissovа

Rashkov

Boyanov³

et al. 2011

Arch Osteoporos

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Section: Risk Factors For Osteoporosis and 10-year Absolute Fracture supporting

confidence: 68%

Femoral neck bone mineral density and 10-year absolute fracture risk in a national representative sample of Bulgarian women aged 50 years and older

Borissovа

Rashkov

Boyanov³

et al. 2011

Arch Osteoporos

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show abstract

“…Yun Zhan and colleagues, in a study of 11,075 adults from the National Health and Nutrition Examination Survey (NHANES), suggested that BMI may be a potential factor affecting the mechanism of bone density due to socioeconomic status [3] . Previous research has shown a close relationship between the development of osteoporosis in perimenopausal women and factors such as age [4] [5] , number of childbirths [6] , family history of osteoporosis [7] , BMI [8] [9] , and regular physical exercise [10] . By including 14 factors in the logistic regression model, the results of this study align with trends observed in previous research conclusions.…”

Section: Discussionmentioning

confidence: 99%

Construction and Validation of Predictive Model for Decreased Bone Density in Premature Ovarian Insufficiency

2024

FMSR

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Premature ovarian insufficiency (POI) is an endocrine disorder that affects women of childbearing age. It is characterized by premature ovarian failure, leading to decreased estrogen levels and increased gonadotropin levels. POI not only impacts reproductive health but is also associated with various long-term health issues, particularly osteoporosis due to decreased estrogen protection, making individuals more susceptible to developing osteoporosis. This study utilized a retrospective cohort study design, including patients diagnosed with POI at the First Affiliated Hospital of Henan Polytechnic University during a certain period. Through detailed medical history collection, bone density measurements, and assessment of other relevant factors, we analyzed potential risk factors associated with decreased bone density caused by POI. Multivariable logistic regression analysis was used to identify independent risk factors, upon which a predictive model was constructed. The results showed that a total of 198 POI patients were included in the study, among whom 54 (34.8%) had decreased bone density. Multivariable analysis revealed that age, parity, family history of osteoporosis, BMI, and regular physical exercise were significantly associated with decreased bone density. Based on these factors, we developed a predictive model and evaluated its predictive performance using the receiver operating characteristic (ROC) curve, with an area under the ROC curve of 0.953 (95% CI: 0.924-0.983), indicating good predictive accuracy.

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“…According to a cross‐sectional study in Spanish menopausal women, Martinez et al . () demonstrated that the most common diseases associated with risk of osteoporosis included chronic hepatopathy, Cushing's syndrome, hyperthyroidism, malabsorption, type I diabetes mellitus, RA, Parkinson's disease, and gastrectomy. Although neurological disabilities such as cerebral palsy may affect bone health, a correlation between neurological disabilities and osteoporosis was not found.…”

Section: Discussionmentioning

confidence: 99%

Osteoporosis is associated with antiepileptic drugs: a population‐based study

Wu¹,

Sheu²,

Lin

2014

Epileptic Disorders

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Controversy remains regarding the risk of bone abnormalities due to enzyme-inducing antiepileptic drugs (EIAEDs) and non-enzymeinducing antiepileptic drugs (NEIAEDs). This case-control study aimed to investigate the possible association between osteoporosis and epilepsy disease and AEDs therapy using a population-based dataset in Taiwan. We first identified 48,102 cases, ≥18 years of age, who received a first-time diagnosis of osteoporosis, and then randomly selected 144,306 controls. We used conditional logistic regression analyses to compute the odds ratio (OR) and corresponding 95% confidence interval (CI) to compare a previous diagnosis of epilepsy between cases and controls. We found that of the 192,408 sampled subjects, epilepsy was found in 117 (0.24%) cases and 240 (0.17%) controls (p<0.001). Cases were found to be more likely to have previously been diagnosed with epilepsy than controls (OR: 1.41, 95% CI: 1.11∼1.78, p<0.01), after taking confounders into consideration. Furthermore, we found that, compared to controls, the adjusted OR of cases in which enzyme-inducing AEDs had been prescribed was 2.06 (95% CI: 1.43∼2.95). A higher proportion of cases with prescribed NEIAED was also found (OR: 2.09, 95% CI: 1.49∼2.92) compared to controls. This study demonstrates that patients with osteoporosis were more likely to have epilepsy and receive EIAED or NEIAED treatment. For patients with epilepsy who take AEDs, attention should be paid to the adverse effects of osteoporosis.

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Assessing osteoporosis risk factors in Spanish menopausal women

Abstract: A high prevalence of women taking osteoporosis risk-related medication was observed in our study. There was correlation between the menopausal symptoms' degree of severity and the risk of suffering from osteoporosis.

Cited by 15 publications

References 38 publications

Femoral neck bone mineral density and 10-year absolute fracture risk in a national representative sample of Bulgarian women aged 50 years and older

Femoral neck bone mineral density and 10-year absolute fracture risk in a national representative sample of Bulgarian women aged 50 years and older

Construction and Validation of Predictive Model for Decreased Bone Density in Premature Ovarian Insufficiency

Osteoporosis is associated with antiepileptic drugs: a population‐based study

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