Assessing patient preferences in heart failure using conjoint methodology

Pisa, G; Eichmann, F.; Hupfer, Stephan

doi:10.2147/ppa.s88167

Cited by 16 publications

(14 citation statements)

References 16 publications

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“…Because of the limitations in daily lives and activities, although they still wished to live their lives or do activities as they were used to, they could not do the routine. Patients with HF very commonly reported limitations in their daily lives and activities due to HF symptoms and impaired functional status, and the impact in prior studies (Ahmad et al, 2016; Heo, Lennie, Okoli, & Moser, 2009; Pisa, Eichmann, & Hupfer, 2015). This fact may, in part, explain high prevalence of negative emotions in this population.…”

Section: Discussionmentioning

confidence: 96%

Patients’ Beliefs About Causes and Consequences of Heart Failure Symptoms

et al. 2019

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Patients’ perceptions of the causes and consequences of heart failure (HF) symptoms may impact effective self-management. The purpose of this study was to describe and explore patients’ perceptions of HF symptom status and the causes and consequences on their daily lives in patients with HF. Descriptive and qualitative data were obtained from 20 patients using a semistructured interview guide. Data were analyzed using content analysis and descriptive statistics. Participants reported 15 symptoms (median = 4). Five themes were (a) multiple causes and multiple symptoms; (b) knowing some causes, but still unclear; (c) not being able to live life as previously did; (d) facing emotional distress due to HF symptoms; and (e) development of new priorities and lifestyles. The findings demonstrate that all participants perceived considerable difficulties living with HF symptoms. More comprehensive interventions need to be delivered to patients to manage multiple causes and symptoms effectively.

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Section: Discussionmentioning

confidence: 96%

Patients’ Beliefs About Causes and Consequences of Heart Failure Symptoms

et al. 2019

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“…This method has now been applied to the study of patients' and physicians' health care preferences and decision making. [14][15][16] In this context, a medical decision or intended action is modeled as a function of potentially influential factors, or attributes, in the clinical situation and/or patient. These attributes are systematically varied across multiple case scenarios, which are then presented to study participants.…”

Section: Methodsmentioning

confidence: 99%

Influence of Maternal Factors in Neonatologists' Counseling for Periviable Pregnancies

2017

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Neonatologists have varying counseling practices for women with threatened periviable pregnancies. Previous research has suggested this variability may be influenced by social and economic factors of the mother. The objective of this study was to determine the relative influence of maternal factors in counseling recommendations for periviable pregnancies. A national cohort of neonatologists was sent a web-based survey. Five maternal characteristics were varied across eight vignettes: age, education, race, parity, and pregnancy "intendedness." Following each vignette, participants reported their likelihood to recommend full resuscitation versus comfort care. Conjoint analysis was used to assess the relative influence of each factor on respondents' recommendations. Responses from 328 neonatologists were included. Of the five tested maternal characteristics, parity and intendedness had the highest importance scores (40.2 and 35.0), followed by race, education, and age. If parents requested resuscitation, respondents were highly likely to comply with preferences, with little variation across vignettes. Fetal-specific factors such as gestational age and estimated weight are known to influence counseling and decision making for extremely preterm infants. Our results suggest that maternal factors may also influence counseling practices, although physicians are likely to comply with parental preferences regardless of maternal factors. Future research should identify how maternal characteristics impact actual counseling practices.

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“…Symptoms (breathlessness, fatigue, and fluid retention) appear slowly and worsen over time,1, 2 which leads to a significant impact on patient's quality of life 3, 4, 5…”

Section: Introductionmentioning

confidence: 99%

“…Symptoms (breathlessness, fatigue, and fluid retention) appear slowly and worsen over time, 1,2 which leads to a significant impact on patient's quality of life. [3][4][5] In Germany, it is estimated that 1.6 million patients suffer from CHF with 200 000-300 000 incident cases per year and increases with age. 6 CHF is the most common reason for hospital admissions with increasing numbers over the past 10 years from 306 736 in 2005 to 432 893 in 2014.…”

Section: Introductionmentioning

confidence: 99%

Budget impact of intravenous iron therapy with ferric carboxymaltose in patients with chronic heart failure and iron deficiency in Germany

Theidel¹,

Väätäinen

Martikainen

et al. 2017

ESC Heart Failure

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AimsTreatment of iron deficiency (ID) in patients with heart failure (HF) with intravenous iron substitution [ferric carboxymaltose (FCM)] has previously shown significant improvements in exercise capacity, New York Heart Association (NYHA) functional class, quality of life, and reduction of hospitalization. The aim of this study was to estimate the budget impact of FCM treatment for patients with HF and ID.Methods and resultsIndividual patient data from four double‐blind randomized controlled trials were pooled for this analysis. Expected outcomes were modelled for a treatment period of 1 year, using multivariate statistical methods. Associated unit costs were derived from claims data. Budget impact was calculated from the perspective of the Statutory Health Insurance. Multiple deterministic sensitivity analyses were performed. The annual budget impact for therapy with FCM vs. no‐iron therapy was €2 735 505 and €2 695 474 for 1000 patients, respectively, resulting in additional annual costs of €40.03 for each treated patient. Main costs drivers are the FCM treatment cost and cost of hospitalizations due to HF worsening. FCM therapy compared with no‐iron therapy resulted in reduced cost per 1000 patients: for reduced hospitalization due to HF worsening (52 vs. 129 hospitalizations amounting to €230 591 vs. €597 078), for reduced other medication (€1 611 007 vs. €1 679 908), fewer outpatient visits (€332 523 vs. €378 019), and home visits (€29 627 vs. €40 469). Sensitivity analyses showed robustness of the results.ConclusionsTherapy with FCM has a minimal budget impact of €40 031 per 1000 patients per year. This budget impact translates into reduced and shorter hospitalizations and improved symptomatic status of the patients.

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Assessing patient preferences in heart failure using conjoint methodology

Cited by 16 publications

References 16 publications

Patients’ Beliefs About Causes and Consequences of Heart Failure Symptoms

Patients’ Beliefs About Causes and Consequences of Heart Failure Symptoms

Influence of Maternal Factors in Neonatologists' Counseling for Periviable Pregnancies

Budget impact of intravenous iron therapy with ferric carboxymaltose in patients with chronic heart failure and iron deficiency in Germany

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