Assessing patient-rated vs. clinician-rated adherence to the therapy in treatment resistant schizophrenia, schizophrenia responders, and non-schizophrenia patients

The influence of adherence to antipsychotics medication on the quality of life among patients with schizophrenia in Indonesia

“…This study suggests that people who experience absent to mild side effects tend to comply with their medication. In accordance with other studies, side effects are one of the predictors of medication adherence . A study finds that patients experiencing side effects are statistically and significantly more likely than others to be nonadherent .…”

“…In accordance with other studies, side effects are one of the predictors of medication adherence. 18,27 A study TA B L E 2 Difference history of illness and medication factor in medication adherence and quality of life (n = 139) finds that patients experiencing side effects are statistically and significantly more likely than others to be nonadherent. 27 The burden of side effects has been extensively explored as a predictor of poor medication adherence.…”

“…However, previous study suggests that many patients with schizophrenia are reported to experience dissatisfaction with mental health care providers and that a lack of access significantly predicted medication omission . Besides, poor attitude toward antipsychotic medication is as predictors of nonadherence to antipsychotic medications . In Indonesia, relapse patient with schizophrenia show a high nonadherence toward medication .…”

“…16 Besides, poor attitude toward antipsychotic medication is as predictors of nonadherence to antipsychotic medications. 17,18 In Indonesia, relapse patient with schizophrenia show a high nonadherence toward medication. 19 A qualitative study indicates that disobedience of treatment is associated with economic factors, endless conflict between couples, continuous family conflict, and depression from unmet needs, and these are also the leading causes of relapse and readmission among inpatients with schizophrenia.…”

Disease Severity in Treatment Resistant Schizophrenia Patients Is Mainly Affected by Negative Symptoms, Which Mediate the Effects of Cognitive Dysfunctions and Neurological Soft Signs

“…For all patients, the following set of clinical-demographic data were recorded: age; gender; education years; age at disease onset (AaO); duration of illness (DoI); age at first psychiatric evaluation; history of substance, alcohol, or drug abuse; everyday living functional milestones ( 4 ). The following rating scales were administered by two experienced raters: the Clinical Global Impression-Severity (CGI-S); the Positive and Negative Syndrome Scale (PANSS); the Neurological Evaluation Scale (NES) ( 10 ); the Drug Attitude Inventory ( 11 ).…”