Assessing quality of life in patients with colorectal cancer: An update of the EORTC quality of life questionnaire

Gujral, Sameer; Conroy, Thierry; Fleissner, Claudia; Sezer, Orhan; King, PM; Avery, Kerry; Sylvester, P. A.; Koller, Michael; Sprangers, Mag; Blazeby, Jane M

doi:10.1016/j.ejca.2007.04.005

Cited by 179 publications

(149 citation statements)

References 29 publications

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“…In a recent study updating the QLQ-CR38 resulted in a hypothetical instrument, the QLQ-CR29, this item was reworded as other gastrointestinal modules (''Have you worried about your weight being too low?'') [22,23].…”

Section: Discussionmentioning

confidence: 97%

“…Large-scale testing involved 117 Dutch patients, but the module was not tested in a large international group to formally determine its validity and cross-cultural applicability. However, the QLQ-CR38 is now widely used in clinical trials (especially for rectal cancer), but some problems related to lack of specificity and missing data have been reported [18][19][20][21][22]. In our previous study of rectal cancer survivors [18], the QLQ-CR38 failed to detect a difference between patients with and without stoma in terms of body image, micturition, gastrointestinal symptoms or sexual life, but this was not the case for our current study of different treatment groups of CRC patients.…”

Section: Discussionmentioning

confidence: 98%

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Validation of the French version of the colorectal-specific quality-of-life questionnaires EORTC QLQ-CR38 and FACT-C

Rotonda¹,

Conroy

Mercier³

et al. 2008

Qual Life Res

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 98%

Validation of the French version of the colorectal-specific quality-of-life questionnaires EORTC QLQ-CR38 and FACT-C

Rotonda¹,

Conroy

Mercier³

et al. 2008

Qual Life Res

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“…[22][23][24] All scales were compared using Student's t-test with stage-matched and unmatched published EORTC reference values for patients with colorectal cancer produced by the EORTC with pooled results from clinical trials and epidemiological studies. QOL results were also compared to the QOL score following conventional APE in studies identified by Cornish et al in their meta-analysis.…”

Section: Methodsmentioning

confidence: 99%

Early experience with laparoscopic extralevator abdominoperineal excision within an enhanced recovery setting: analysis of short-term outcomes and quality of life

Vaughan-Shaw¹,

King²,

Cheung³

et al. 2011

annals

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INTRODUCTION Conventional abdominoperineal excision for low rectal cancer has a higher local recurrence and reduced survival compared to anterior resection. An extralevator abdominoperineal excision (ELAPE) may improve outcome through removal of increased tissue in the distal rectum. Experience with ELAPE is limited and no studies have reported on quality of life (QOL) following this procedure. We describe a minimally invasive approach to ELAPE within an enhanced recovery programme, and present short-term results and QOL analyses. METHODS All laparoscopic ELAPEs were included in a prospective database. Demographics, intra-operative and post-operative outcomes were evaluated. Postoperative QOL was assessed using the European Organisation for Research and Treatment of Cancer (EORTC) questionnaires QLQ-C30 and QLQ-CR29. RESULTS Thirteen laparoscopic ELAPEs were performed over a two-year period. All were enrolled in an enhanced recovery programme. The median age was 76. The median tumour height was 20mm (range: 0–50mm) from the dentate line and all patients received neoadjuvant treatment. The median duration of surgery was 300 minutes (range: 120–488 minutes), the mean blood loss was 150ml and one procedure was converted to open surgery. There was no circumferential resection margin involvement or tumour perforation. The median duration of use of intravenous fluid, patient controlled analgesia and urinary catheterisation was 2, 2 and 2.5 days respectively and the median length of hospital stay was 7.5 days. Two patients developed perineal wound dehiscence. QOL analysis revealed high global health status (90.8), physical (91.3), emotional (98.3) and social functioning (100) scores, which compared favourably with EORTC reference values and published QOL scores following conventional abdominoperineal excision. CONCLUSIONS Laparoscopic ELAPE within an enhanced recovery setting is a feasible and safe approach with acceptable short-term outcomes and post-operative quality of life.

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“…There are now several valid measures of HRQL suitable to use in patients with CRC [3][4][5][6][7]. Although these instruments are widely available, careful application of the tools in clinical studies is needed to produce reliable and clinically useful results [8,9].…”

Section: Introductionmentioning

confidence: 99%

Quality of life after surgery for colorectal cancer: clinical implications of results from randomised trials

Gujral

Avery

Blazeby

2007

Support Care Cancer

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Assessing quality of life in patients with colorectal cancer: An update of the EORTC quality of life questionnaire

Cited by 179 publications

References 29 publications

Validation of the French version of the colorectal-specific quality-of-life questionnaires EORTC QLQ-CR38 and FACT-C

Validation of the French version of the colorectal-specific quality-of-life questionnaires EORTC QLQ-CR38 and FACT-C

Early experience with laparoscopic extralevator abdominoperineal excision within an enhanced recovery setting: analysis of short-term outcomes and quality of life

Quality of life after surgery for colorectal cancer: clinical implications of results from randomised trials

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