Assessing screening instruments and thresholds to detect risk of depression in diabetes patients, a brief report

Liu, Xiaona; Boogaard, Laura H.; Erasmus, Vicki; Sybrands, Eric; Buijks, Hanneke; Mackenbach, Johan P.; Polinder, Suzanne

doi:10.1016/j.pcd.2018.11.006

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Valid detection of depression in diabetes is important (Petrak et al., 2015). Among the various screening methods, the WHO‐5 (World Health Organization Well‐being Index‐5), BDI‐II (Beck Depression Inventory‐II), PHQ‐9 (Patient Health Questionnaire‐9), and PAID (Problem Areas in Diabetes Scale) are widely employed (Liu, Boogaard, et al., 2019; Rauwerda et al., 2018). The stigma surrounding depression often causes patients to struggle with guilt for “feeling that way” and shy away from seeking help, especially psychiatric.…”

Section: Possible Intervention Management and Treatment Strategiesmentioning

confidence: 99%

Pathophysiology linking depression and type 2 diabetes: Psychotherapy, physical exercise, and fecal microbiome transplantation as damage control

Subba

Sandhir

Singh

et al. 2021

Eur J of Neuroscience

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Diabetes increases the likelihood of developing depression and vice versa. Research on this bidirectional association has somewhat managed to delineate the interplay among implicated physiological processes. Still, further exploration is required in this context. This review addresses the comorbidity by investigating suspected common pathophysiological mechanisms. One such factor is psychological stress which disturbs the hypothalamic–pituitary–adrenal axis causing hormonal imbalance. This includes elevated cortisol levels, a common biomarker of both depression and diabetes. Disrupted insulin signaling drives the hampered neurotransmission of serotonin, dopamine, and norepinephrine. Also, adipokine hormones such as adiponectin, leptin, and resistin and the orexigenic hormone, ghrelin, are involved in both depression and T2DM. This disarray further interferes with physiological processes encompassing sleep, the gut–brain axis, metabolism, and mood stability. Behavioral coping mechanisms, such as unhealthy eating, mediate disturbed glucose homeostasis, and neuroinflammation. This is intricately linked to oxidative stress, redox imbalance, and mitochondrial dysfunction. However, interventions such as psychotherapy, physical exercise, fecal microbiota transplantation, and insulin‐sensitizing agents can help to manage the distressing condition. The possibility of glucagon‐like peptide 1 possessing a therapeutic role has also been discussed. Nonetheless, there stands an urgent need for unraveling new correlating targets and biological markers for efficient treatment.

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Section: Possible Intervention Management and Treatment Strategiesmentioning

confidence: 99%

Pathophysiology linking depression and type 2 diabetes: Psychotherapy, physical exercise, and fecal microbiome transplantation as damage control

Subba

Sandhir

Singh

et al. 2021

Eur J of Neuroscience

View full text Add to dashboard Cite

show abstract

Interprofessional education clinics and improved outcomes for primary care patients with diabetes

Rowe

Congdon

Pittman

et al. 2021

Journal of Interprofessional Education & Practice

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Assessing screening instruments and thresholds to detect risk of depression in diabetes patients, a brief report

Cited by 2 publications

References 17 publications

Pathophysiology linking depression and type 2 diabetes: Psychotherapy, physical exercise, and fecal microbiome transplantation as damage control

Pathophysiology linking depression and type 2 diabetes: Psychotherapy, physical exercise, and fecal microbiome transplantation as damage control

Interprofessional education clinics and improved outcomes for primary care patients with diabetes

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