Assessing the antioxidative properties and chemical composition ofLinaria vulgarisinfusion

Abstract

The ability of Linaria vulgaris (Scrophulariaceae) infusion to act as a scavenger of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, reactive oxygen species (superoxide radical, hydroxyl radical, hypochlorous acid (HOCl)) and nitric oxide was investigated. The obtained data indicate that the infusion has a good scavenging activity against superoxide radical and is a very potent nitric oxide and DPPH scavenger. In hydroxyl radical assay a pro-oxidant capacity was noticed, especially for concentrations higher than 31.25 microg mL(-1). No effect was found against HOCl. A phytochemical study of this extract was also performed. The HPLC/UV analysis allowed the identification and quantification of eight organic acids (oxalic, aconitic, citric, ketoglutaric, ascorbic, malic, shikimic and fumaric acids). The phenolic composition of the lyophilised infusion was also determined by HPLC/DAD and four compounds were quantified, but, despite its high content, only linarin was managed to be identified.

Exploiting Catharanthus roseus roots: Source of antioxidants

“…This value proved to be lower than any other plant part studied before, namely leaves (IC 50 447 lg/ml), stems (IC 50 476 lg/ml), seeds (IC 50 265 lg/ml) or petals (IC 50 197 lg/ml) . As the conditions used in the work herein were the same as described in a previous evaluation of antioxidant potential of other plant parts, direct comparisons can be made (Table 2) analysed by the same method, this matrix proved to be more active: for Linaria vulgaris the IC 50 value was 354 lg/ml (Vrchovská et al, 2008), Brassica rapa var. rapa exhibited IC 50 of 557 lg/ml (Pereira, Noites, et al, 2009) and Cydonia oblonga Miller pulp an IC 50 of 1700 lg/ml (Silva et al, 2004).…”

Antimicrobial, Cytotoxic, and Antioxidant Potential of a Novel Flavone “6,7,4′‐Trimethyl Flavone” Isolated from Wulfenia amherstiana

“…e results revealed that this plant possessed remarkable scavenging capacity for superoxide, very intense scavenger of nitric oxide, and 2,2-diphenyl-1-picrylhydrazyl (DPPH) [38].…”

Linarin, a Glycosylated Flavonoid, with Potential Therapeutic Attributes: A Comprehensive Review

“…This compound was isolated from two Linaria species L. japonica, L. vulgaris, and L. kurdica subsp. eriocaly, while the whole parts were chromatographed [62][63][64].…”

“…The lyophilized infusion prepared from Linaria vulgaris Mill. has previously been experimented through HPLC-UV and LN was quantified with a significant content of 3.84 g/kg drug [63].…”