Assessing the clinical utility of in vitro fertilization with intracytoplasmic sperm injection in human immunodeficiency virus type 1 serodiscordant couples: report of 113 consecutive cycles

HIV couples' anxiety and risk taking during ART

“…The data presented here show that although the risk of HIV-1 transmission to the woman is reduced to almost nil by IUI with processed semen (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14), the fear of HIV-1 transmission among these couples is not proportionally reduced, and anxiety is still present among these couples.…”

“…Since then, more than 3,000 treatments have been performed, mainly in Europe, leading to the birth of more than 500 children. Transmission of HIV to women by the inseminations has never been reported (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14).…”

Systematic review of the effectiveness and safety of assisted reproduction techniques in couples serodiscordant for human immunodeficiency virus where the man is positive

“…The maximum viral load was 49.000, and the minimum CD4 þ T-cell count was 400 (6,(12)(13)(14)(15)(16)(17). Four studies reported the use of antiretroviral treatment with no mention of the type of the drug prescribed (5,6,13,17).…”

“…Advances in semen preparation (5) were followed by the use of intrauterine insemination (IUI) in HIV serodiscordant couples, which resulted in a low risk of transmission. Other studies reported the use of alternative techniques such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) to reduce the risk of HIV exposure to the woman and to the gamete (5,6).…”

Sperm washing to prevent HIV transmission from HIV-infected men but allowing conception in serodiscordant couples

“…Since then, spermwashing techniques have substantially changed the paradigm of fathering children in sero-discordant couples for male HIV infection. Also, different individual studies have reinforced the methodological (Marina 1998;Anderson 1999; and clinical issues (Ohl 2003;Pena 2003;Bujan 2004;Garrido 2004;Nicopoullos 2004;Mencaglia 2005) of sperm washing in preventing HIV transmission but allowing conception in HIV sero-discordant couples. Furthermore, an estimate of the use of sperm washing in Europe (Gilling-Smith 2000; Savasi 2006) provided additional evidence of the clinical value of this procedure.…”