Assessing the effects of air pollution and residential greenness on frailty in older adults: a prospective cohort study from China

Guo, Xianwei; Su, Wenqi; Wang, Xingyue; Hu, Wenjing; Meng, Jia; Ahmed, Mubashir Ayaz; Qu, Guangbo; Sun, Yehuan

doi:10.1007/s11356-023-31741-9

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2024

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Cited by 2 publications

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Effects of air pollutants exposure on frailty risk: A systematic review and meta-analysis

Ding,

Kou,

Feng

et al. 2024

Environmental Pollution

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Effects of air pollutants exposure on frailty risk: A systematic review and meta-analysis

Ding,

Kou,

Feng

et al. 2024

Environmental Pollution

View full text Add to dashboard Cite

The association between PM2.5 and frailty: Evidence from 122 cities in China and 7 countries in Europe

Wen,

Zhu,

Cao

et al. 2024

Preprint

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Background: The accelerated aging process worldwide is placing a heavy burden on countries. PM2.5 particulate matter exposure is a significant factor affecting human health and is crucial in the aging process. Methods: We utilized data from China Health and Retirement Longitudinal Study (CHARLS) and the Survey of Health, Aging, and Retirement in Europe (SHARE) to study the relationship between PM2.5 exposure and the frailty index. Acquire PM2.5 exposure data for China and Europe, match them according to geographic location within the database. Our study used frailty index to evaluate frailty, which comprises 29 items. We examined the association between PM2.5 and frailty index using fixed-effects regression models and Mendelian randomization (MR) analysis. Results: We first examined the association between PM2.5 and frailty index using fixed-effects regression models, revealing a notable positive link across populations in China (coefficient = 0.0003, P = 0.0380) and Europe (Coefficient = 0.0019, P < 0.0001). This suggests that PM2.5 exposure is a significant risk factor for frailty, leading to accelerated frailty. Moreover, our MR analysis uncovered a possible causal association (OR = 1.2933，95%CI: 1.2045-1.3820, P < 0.0001) between PM2.5 exposure and the frailty index. Conclusions: Our findings indicate that long-term exposure to PM2.5 in the environment is a risk factor for physical frailty and may have a potential causal relationship. Given the rapid global aging trend, it is crucial to focus on how air pollution affects frailty and to combat its negative consequences.

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Assessing the effects of air pollution and residential greenness on frailty in older adults: a prospective cohort study from China

Cited by 2 publications

References 64 publications

Effects of air pollutants exposure on frailty risk: A systematic review and meta-analysis

Effects of air pollutants exposure on frailty risk: A systematic review and meta-analysis

The association between PM2.5 and frailty: Evidence from 122 cities in China and 7 countries in Europe

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