In response to the escalating threats of cybersecurity attacks and breaches, ensuring the development and deployment of secure IT products has become paramount for organizations in their cybersecurity transformation. This work emphasizes the critical need for a comprehensive and secure IT project management life cycle that safeguards products from their initial development stages through decommissioning. The primary objective is to seamlessly integrate security considerations into every facet of IT project management life cycles. This work embraces a cyber-resilient IT project management framework and advocates the inclusion of cybersecurity measures in IT projects and their strategic, organized, continuous, and systematic integration throughout the entire product life cycle. It introduces a pioneering framework that harmonizes the cybersecurity risk management process with the IT project management life cycle. This framework delineates a methodical sequence of steps, each encompassing a distinct set of activities. The effectiveness and practical applicability of the proposed framework were validated through a comprehensive case study focused on the Personal Health Record (PHR) system. The PHR case study served as a real-world scenario to assess the framework’s ability to address cybersecurity challenges in a specific domain. The results of the experiment demonstrated the framework’s efficacy in enhancing the security posture of IT projects, showcasing its adaptability and scalability across diverse applications.