Assessing the optimal imaging modality in the diagnosis of jaw osteomyelitis. A meta-analysis

Tiwari, Preeti; Bera, Rathindra Nath; Kanojia, Shweta; Chauhan, Nishtha; Hirani, Mehul Shashikant

doi:10.1016/j.bjoms.2020.11.012

Cited by 9 publications

(2 citation statements)

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“…The diagnosis of CRMO is usually confirmed by bone biopsy after excluding other diseases, such as bacterial osteomyelitis, scurvy, metabolic disorders, and malignant diseases [1] , [2] , [3] . Imaging studies, such as radiography, computed tomography, magnetic resonance imaging (MRI), and bone scintigraphy, are useful for diagnosing CRMO and providing a roadmap for possible biopsy [ 1 , 2 , [4] , [5] , [6] ].…”

Section: Introductionmentioning

confidence: 99%

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Ultrasound evaluation of inflammation in patients with chronic recurrent multifocal osteomyelitis involving the mandible: report of three cases

Hosokawa

Ohnishi

Sato

et al. 2022

Radiology Case Reports

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Chronic recurrent multifocal osteomyelitis (CRMO) is aseptic and can be diagnosed by excluding other diseases, such as bacterial osteomyelitis, scurvy, metabolic disorders, and malignant diseases; therefore, bone biopsy is usually performed to confirm the diagnosis. To prevent misdiagnosis, the appropriate timing and location for biopsy should be determined from an active phase of inflammation. We presented 3 cases of CRMO involving the mandible: Case 1: A 2-year-old girl diagnosed with CRMO in the chronic phase. A sonogram showed a slightly low echoic area adjacent to the bone cortex. Pathological examination revealed a slight accumulation of leukocytes and plasma cells, as well as predominant fibrous stroma. Case 2: A 9-year-old girl diagnosed with CRMO with massive new osteoid formation. A sonogram showed a massive inhomogeneous low echoic area adjacent to the bone cortex. Pathological examination revealed massive osteoid formation and scattered inflammatory cells infiltration. Case 3: A 3-year-old girl diagnosed with CRMO in the active phase. A sonogram showed a massive hypoechoic area adjacent to the bone cortex and hyperechogenicity associated with a muscular and subcutaneous edema. Pathological examination revealed massive bone destruction and neutrophils infiltration within damaged osteoid. Ultrasound was able to visualize the degree of inflammation in the mandible corresponding to that of the surrounding soft tissue in all 3 cases. Therefore, ultrasound would be useful in determining the appropriate timing and location for bone biopsy.

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Section: Introductionmentioning

confidence: 99%

“…Until now, although there have been few reports focusing on imaging modalities for diagnosing CRMO, ultrasound has not been used for this purpose [ 1 , 2 , [4] , [5] , [6] , [7] , [8] , [9] ]. Ultrasound is a useful imaging modality that offers high resolution and zero radiation exposure.…”

Section: Introductionmentioning

confidence: 99%