Assessing the prevalence and antibiotic susceptibility patterns of S. aureus bacteria isolated from Iraqi women with vaginosis

Abstract

Bacterial vaginosis (BV) is a common infection that occurs when the number of lactobacillus spp. bacteria (vaginal flora) decreases in the vaginal canal. The study aimed to determine the prevalence of Staphylococcus aureus within vaginosis in order to emphasize the importance of early detection and treatment. Totally, 90 vaginal swabs were collected using speculum and swabbing. The vaginal swabs were subjected to standard microbiological testing, which included microscopy, cultures (Blood agar and Mannitol salt agar), and antibiotic sensitivity testing. The results showed that out of 90 samples, only 40 S.aureus isolates were collected. S. aureus isolates showed maximum sensitivity to gentamicin and high resistance to Cefoxitin, Erythromycin, Azithromycin, and moderate resistance to Clindamycin, Rifampicin, Ciprofloxacin, and Doxycycline. Regarding molecular detection of mecA, the results revealed that out of 40 S. aureus isolates only 22 isolates have this gene. This study concludes that S. aureus (MRSA) was the most prevalent within vaginosis with high resistance to most antibiotics.

Phenotypic Resistance of (MRSA) Clinical Isolates to Some Macrolide Antibiotic Groups

“…Conclusions from the current study found that the isolates were resistant to doxycycline at a rate of (3.1%), which is not comparable to the findings of [26,27], who recorded a resistance rate of doxycycline of 20.6% and 30%, respectively. azithromycin had a resistance rate of 28 (87.5%) of MRSA isolates, which was less low than the results of [28], who published that the resistance rate of MRSA isolates against azithromycin was 92.5%.…”