The purpose of the article is to evaluate the effectiveness of the "green" growth policy pursued at the regional level. An analysis of various approaches to assessing the sustainability of the socio-economic development of the region is presented. To achieve this purpose, a comprehensive methodology was used, considering territorial factors and sectoral conditions for the development of the regions. Domestic and foreign experience in assessing the sustainability and effectiveness of the territory development were analyzed. Existing methods for assessing the region stability are studied. An integral indicator of sustainable development of the region is calculated, which includes indicators of economic, environmental, and social sustainability. The typology of Kazakhstan regions has been carried out according to the level of their environmental and economic development for the purposes of developing an effective environmental and innovation policy. It has been proved that the list of socio-economic indicators used in the calculation of the integral index makes it possible to determine with a sufficient degree of certainty the effectiveness of the ongoing regional development policy from the standpoint of observing the principles of "green" growth. It has been revealed that the modern model of socio-economic development of the country and its regions requires further efforts to develop adequate indicators of "green" development that consider economic, social and environmental components in a balanced way. The empirical conclusions of the work can find practical application in the process of developing an effective environmental and economic regional policy.