Assessing the role of mitonuclear interactions on mitochondrial function and organismal fitness in naturalDrosophilapopulations
S Bettinazzi,
J Liang,
E Rodriguez
et al.
Abstract:Mitochondrial metabolism is regulated by a series of enzyme complexes, whose function depends on effective interactions between proteins and RNA encoded by the mitochondrial and nuclear genomes. These epistatic interactions are in turn highly sensitive to the environment. Many studies have found that mitochondrial haplotype frequencies of various taxa associate with latitude or altitude, leading to the hypothesis that mitochondrial genomes may respond to thermal selection and contribute to local adaptation. We… Show more
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