Assessing the sedation effect of dexmedetomidine during hysteroscopic surgery

Hu, Bailong; Zhou, Haiyan; Zou, Xiaohua

doi:10.1111/jcpt.12824

J Clin Pharm Ther

2019

DOI: 10.1111/jcpt.12824

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Assessing the sedation effect of dexmedetomidine during hysteroscopic surgery

Bailong Hu

Haiyan Zhou

Xiaohua Zou

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“…It has the characteristics of quick onset, short half-life, etc., and patients can recover quickly after stopping administration after surgery. Sufentanil is an opioid analgesic with a high affinity for opioid receptors, which can play an ideal analgesic effect while extending the analgesic time [8,9]. In recent years, Sufentanil combined with propofol anesthesia has been applied in some cases of hysteroscopic surgery in our hospital, and relatively ideal results have been obtained.…”

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confidence: 99%

Effect of Sufentanil Combined with Propofol on Hemodynamic Level and Postoperative Recovery of Patients Undergoing Hysteroscopic Surgery

Xu,

Fu,

Zhao

et al. 2023

IJCEMR

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Objective: To investigate and analyze the effects of Sufentanil and propofol on the hemodynamic level and postoperative recovery of patients undergoing hysteroscopic surgery. Method: Eighty patients undergoing elective hysteroscopic surgery at our hospital between January 2021 and November 2022 were selected as the research subjects. They were randomly divided into two groups using a random number table method, with 40 cases in each group. Fentanyl combined with propofol was used as anesthesia for hysteroscopic surgery in the control group, while Sufentanil combined with propofol was used as anesthesia in the study group. The hemodynamic levels, propofol dosage, postoperative recovery, early postoperative pain, and occurrence of adverse reactions were evaluated and compared at different stages of the operation. Results: The heart rate and mean arterial pressure in the study group were lower than those in the control group at the beginning and end of the operation, and the difference was statistically significant (P < 0.05). Comparison of postoperative recovery and early postoperative pain: the dosage of propofol in the study group was less than the control group, the postoperative recovery time was shorter than the control group, and the early postoperative pain score was lower than the control group, the difference was statistically significant (P < 0.05). The incidence of respiratory depression, nausea, vomiting, delirium, abnormal blood pressure and other adverse reactions in the study group was lower than that in the control group, with statistical significance (P < 0.05). Conclusions: The combination of sufentanil and propofol has minimal impact on the hemodynamic stability of patients undergoing hysteroscopic surgery. Additionally, it results in shorter postoperative recovery time and higher application safety.

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confidence: 99%

Effect of Sufentanil Combined with Propofol on Hemodynamic Level and Postoperative Recovery of Patients Undergoing Hysteroscopic Surgery

Xu,

Fu,

Zhao

et al. 2023

IJCEMR

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Authors’ reply to Dr. Bailong’s commentary: Assessing the sedation effect of dexmedetomidine during hysteroscopic surgery

et al. 2019

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Assessing the sedation effect of dexmedetomidine during hysteroscopic surgery

Cited by 2 publications

References 3 publications

Effect of Sufentanil Combined with Propofol on Hemodynamic Level and Postoperative Recovery of Patients Undergoing Hysteroscopic Surgery

Effect of Sufentanil Combined with Propofol on Hemodynamic Level and Postoperative Recovery of Patients Undergoing Hysteroscopic Surgery

Authors’ reply to Dr. Bailong’s commentary: Assessing the sedation effect of dexmedetomidine during hysteroscopic surgery

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