This study investigates a fire weather index (FWI) and its associated components in Australia using the downscaled projects for the Coupled Model Intercomparison Project phase 6 (CMIP6) dataset, aiming to understand how they respond to global warming, particularly associated with different phases of the El Niño-Southern Oscillation (ENSO). In the historical simulation, multimodel mean composite results show positive anomalies of FWI during El Niño and negative anomalies during La Niña over most of Australia relative to the neutral year. At the end of the 21st century under the Shared Socioeconomic Pathways (SSP585 scenario), FWI anomalies increased across Australia; however, ENSO wildfire teleconnections weakened (-4.4%) during El Niño but strengthened (+6.0%) during La Niña, especially in northern Australia. Further examination of the contribution from individual environmental variables that enter the FWI shows that increased temperature and drought conditions with warming in La Niña strengthen positive FWI anomalies, thus making fire more favorable in north and central Australia. The impacts of relative humidity and wind speed anomaly changes also favor fire activity toward the north. These results suggest a more robust modulation of FWI in northern Australia by ENSO in a warmer climate; future efforts to predict wildfire will depend on the model’s ability to predict local climate conditions.