Assessment and initial management of acute kidney injury

Griffiths, Laura; Kanagasundaram, Nigel S.

doi:10.1016/j.mpmed.2011.04.010

Cited by 4 publications

(3 citation statements)

References 33 publications

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“…It was identified a prevalence of patients with elevation in ALP and AAT levels (12.8%) and urea and creatinine levels (21.3%), these elevations show that the animals may present different degrees of renal and hepatic impairment, occurring due to deposition of immunocomplexes in glomerulus (Kumar & Saxena, 2018). A drop in perfusion occurs due to hypovolemia and systemic hypotension, as well as, by lesion in hepatocytes caused by endotoxemia and/or reduced circulation in the liver from dehydration (Feldman & Nelson, 1996;Nunes et al, 2010;Griffiths & Kanagasundaram, 2011;Honório et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Epidemiological indicators of canine piometra: An analysis of main components in the case of cases assisted in the northeast region of Pará

Silva

Salvarani

Coutinho

et al. 2022

RSD

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Pyometra is the endometrial disorder of greatest clinical importance in small animals. The realization of studies with the purpose of obtaining epidemiological data related to the occurrence of pyometra in bitches are fundamental. The objective was to determine epidemiological indicators of canine pyometra using the statistical method of principal component analysis and to characterize the set of parameters that facilitate the diagnosis and a possible clinical-epidemiological profile, through the casuistry attended in university veterinary hospitals in the northeastern region of Pará. A total of 142 medical records in two university veterinary hospitals were consulted. A total of 18 variables were analyzed using principal component analysis (PCA) and descriptive statistics. The PCA identified three groups of epidemiological indicators that together explained 71.05% of the variability of the data. The first group (abdominal pain, abdominal distension, critical condition and leukocytosis), the second (apathy, anorexia, pyometra type, and vaginal discharge) and the third (age, race, parity and pseudocyesis). It was observed that 47.7% of the bitches were five to 10 years old, 63.8% were of undefined breed and 62.4% were nulliparous (p<0.05). The pyometra of the open type presented a frequency of 82.4% (p<0.05). The variables pain, abdominal distension and leukocytosis are indicators of severe stage disease. The variables apathy, anorexia/hyporexia and vaginal secretion are indicators of disease in mild stage and the variables age and race act as epidemiological indicators of predisposition. Moreover, it was identified that the clinical-epidemiological profile of affected animals is of middle-aged, non-breed, nulliparous bitches with open pyometra.

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Section: Discussionmentioning

confidence: 99%

Epidemiological indicators of canine piometra: An analysis of main components in the case of cases assisted in the northeast region of Pará

Silva

Salvarani

Coutinho

et al. 2022

RSD

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“…It has also been suggested that the strict definition of AKI requires the correction of pre-renal azotaemia 5 -the reduction in renal excretory capacity arising from renal under-perfusion. 6 Pre-renal azotaemia is a predictable by-product of a normal, physiological response to reduced effective circulating volume and is readily reversed through volume replacement or vasopressor therapy as no renal cell injury (i.e. AKI) has yet occurred.…”

Section: Discussionmentioning

confidence: 99%

Apparent oliguria following urological surgery

Es²,

Haslam³

et al. 2012

J R Coll Physicians Edinb

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Oliguria is a common feature of acute kidney injury (AKI), but should be interpreted in the context of other biochemical markers when diagnosing and monitoring AKI or considering the need for renal support. We report an unusual case of apparent severe oliguria arising as a result of complex urological pathology and discuss how an understanding of creatinine kinetics raised suspicions of an alternative diagnosis. We discuss the problems caused by an over-reliance on urine output or serum creatinine alone when diagnosing and staging AKI and highlight the need for a more holistic approach.

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“…1 Patients with one or more risk factors should undergo frequent biochemical monitoring and clinical review of fluid balance, volume status and medications. 15 Clinicians often view the management of AKI as challenging because of its perceived complexity. However, studies have demonstrated that, all too often, even the basics in care (such as fluid balance, intravenous fluids and regular blood monitoring) are neglected.…”

Section: Epidemiologymentioning

confidence: 99%

Acute kidney injury: top ten tips

2012

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-Acute kidney injury (AKI) is associated with increased patient morbidity and mortality, and represents a significant financial burden for the NHS. The National Confidential Enquiry into Patient Outcomes and Death (NCEPOD)'s report, Adding insult to injury, demonstrated that only 50% of patients who died from AKI received good care and 30% of patients had predictable and avoidable AKI. It is therefore essential to identify patients at risk of AKI early and to treat patients who develop it promptly. This article proposes how this may be achieved by highlighting ten top tips that describe the points along the patient pathway where it is possible to intervene and prevent or treat AKI. The tips emphasise the importance of good basic medical care and the need for engagement with patients, healthcare professionals and hospital processes. The implementation of these tips in hospitals across the UK could potentially improve patient outcomes and reduce associated costs.

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Assessment and initial management of acute kidney injury

Cited by 4 publications

References 33 publications

Epidemiological indicators of canine piometra: An analysis of main components in the case of cases assisted in the northeast region of Pará

Epidemiological indicators of canine piometra: An analysis of main components in the case of cases assisted in the northeast region of Pará

Apparent oliguria following urological surgery

Acute kidney injury: top ten tips

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