1999
DOI: 10.1016/s0304-3959(98)00138-9
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Assessment and treatment of neuropathic cancer pain following WHO guidelines

Abstract: Neuropathic pain syndromes are one of the major problems of cancer pain treatment. The present study surveys 593 cancer patients treated by a pain service following the WHO guidelines for relief of cancer pain. Of these, 380 presented with nociceptive, 32 with neuropathic and 181 with mixed (nociceptive and neuropathic) pain. In patients with nociceptive, mixed and neuropathic pain, the average duration of evaluated pain treatment was 51, 53 and 38 days, respectively. Non-opioid or opioid analgesics were given… Show more

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Cited by 201 publications
(122 citation statements)
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“…This case adds thoracic outlet obstruction of the subclavian artery with limb ischaemia as a potential risk during park bench positioning. .............................................................................................................................................................................................................. Epidural infusions can be used for the management of selected patients with difficult cancer pain [1][2][3][4]. In patients with infusions lasting more than a few days our experience suggests that pain generally does not recur immediately after catheter removal.…”
Section: Thoracic Outlet Obstruction During Neurosurgical Positioningmentioning
confidence: 97%
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“…This case adds thoracic outlet obstruction of the subclavian artery with limb ischaemia as a potential risk during park bench positioning. .............................................................................................................................................................................................................. Epidural infusions can be used for the management of selected patients with difficult cancer pain [1][2][3][4]. In patients with infusions lasting more than a few days our experience suggests that pain generally does not recur immediately after catheter removal.…”
Section: Thoracic Outlet Obstruction During Neurosurgical Positioningmentioning
confidence: 97%
“…The recommended dose of Intralipid 20% is of course 1.5 ml.kg )1 , not 1.5 mg.kg . Two recent case reports used an even higher dose of 3 ml.kg )1 of lipid with successful outcomes [1,2] so it seems that the key in treating this complication is the delivery of a large bolus of lipid early. Clearly 105 mg of lipid is likely to be insufficient!…”
Section: A Replymentioning
confidence: 99%
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“…The prevalence of pain amongst those with advanced, metastatic cancer reaches 95%, and its intensity ranges between 7-8 in a VRS 1-10 scale, also despite the fact that 92% of these patients receive opioids and 42% adjuvant analgesics. These findings have been attributed to inappropriate doses prescribed, or administration from inappropriate routes, apparently due to insufficient education of physicians and other health care professionals, or even due to fear of undesirable side effects (8,9). Overall, lack or failure of treatment to control cancer pain has been attributed mainly to lack of appropriate knowledge or ineffective individual assessment for pertinent symptoms, resulting in underutilization or improper use of analgesic resources.…”
Section: The Epidemiology Of Cancer Pain Todaymentioning
confidence: 99%