Assessment of a gel‐type chelating preparation containing 1‐hydroxyethylidene‐1, 1‐bisphosphonate

Girard, Sylvain; Paqué, Frank; Badertscher, M; Sener, Beatrice; Zehnder, Matthias

doi:10.1111/j.1365-2591.2005.01021.x

Cited by 60 publications

(62 citation statements)

References 19 publications

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“…Hence, citric acid or EDTA should never be mixed with sodium hypochlorite. The same goes for paste-type EDTA preparations: at a 1:10 ratio, they immediately rid a 1% sodium hypochlorite solution of all hypochlorite (142). The "bubbling effect" or effervescence used to advocate for such products is only proof of the chemical reaction that takes place between hypochlorite on the one hand and EDTA and hydrogen peroxide (if contained in the paste-type chelating product) on the other hand, resulting in evaporating gas (141).…”

Section: Chelator Solutionsmentioning

confidence: 97%

Root Canal Irrigants

Zehnder

2006

Journal of Endodontics

1,579

1,508

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Section: Chelator Solutionsmentioning

confidence: 97%

Root Canal Irrigants

Zehnder

2006

Journal of Endodontics

1,579

1,508

View full text Add to dashboard Cite

“…Moreover, alternative chemicals or combinations to remove the smear layer have been introduced (12)(13)(14)(15)(16)(17)(18)(19). One recently raised issue regarding the use of EDTA or citric acid is that these agents strongly react with sodium hypochlorite, thus rendering the latter agent ineffective (9,14,18,19).…”

Section: Introductionmentioning

confidence: 99%

Longitudinal Co-site Optical Microscopy Study on the Chelating Ability of Etidronate and EDTA Using a Comparative Single-tooth Model

De‐Deus¹,

Zehnder²,

Reis³

et al. 2008

Journal of Endodontics

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Longitudinal co-site optical microscopy study on the chelating ability of etidronate and EDTA using a comparative single-tooth model AbstractIn the present study the smear layer dissolution kinetics of 18% etidronate (HEBP), 9% HEBP, and 17% ethylenediaminetetraacetic acid (EDTA) on human dentin were quantitatively and longitudinally analyzed by using a single-tooth comparative model. Coronal dentin disks were prepared from 3 maxillary human molars. A standardized smear layer was produced on the pulpal side of each disk. The smear layer-covered surface was divided into 3 similar areas. Each of these was then exposed to 1 of the 3 irrigants under investigation, whereas the others were covered with adhesive tape. Co-site image sequences of the areas under investigation were obtained after several cumulative demineralization times. Sixteen images were obtained from each dentin area of each tooth for each experimental time at 1000x magnification. An image processing and analysis sequence measured sets of images, providing data of area fraction for thousands of tubules over time and allowing us to quantitatively follow the effect of the chelating substances. The Kruskal-Wallis H test and Dunn multiple comparison test were used to analyze the data. Overall, it can be concluded that the demineralization kinetics promoted by both 9% HEBP and 18% HEBP were significantly slower than those of 17% EDTA (P < .05). In addition, the single-tooth model is advantageous over the first co-site optical microscopy dentin assessments when different chelator solutions are compared. Longitudinal Co-site Optical Microscopy Study of the Chelating Ability of HEBP and EDTA Using a Comparative Single-tooth Model AbstractIn the present study the smear layer dissolution kinetics of 18% HEBP, 9% HEBP and 17%EDTA on human dentin were quantitatively and longitudinally analyzed using a singletooth comparative model. Coronal dentin disks were prepared from three maxillary human molars. A standardized smear layer was produced on the pulpal side of each disk. The smear layer-covered surface was divided into three similar areas. Each of these was then exposed to one of the three irrigants under investigation, while the others were covered with adhesive tape. Co-site image sequences of the areas under investigation were obtained after several cumulative demineralization times. Sixteen images were obtained from each dentin area of each tooth for each experimental time, at 1000x magnification. An image processing and analysis sequence measured sets of images, providing data of area fraction for thousands of tubules over time, allowing to quantitatively follow the effect of the chelating substances. The Kruskal-Wallis H-test and Dunn's multiple comparison test were used to analyze the data. Overall, it can be concluded that the demineralization kinetics promoted by both 9% HEBP and 18% HEBP were significantly slower than those of 17% EDTA (p < 0.05). In addition, the single-tooth model is advantageous over the first co-site optical microscopy dentin asse...

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“…Instead, these chemicals immediately reduce the hypochlorite to chloride and thus render it nonreactive. The only chemical with decalcifying capacity identified thus far as being compatible with NaOCl, at least in the short-term, is 1-hydroxyethylidene-1, 1-bisphosphonate (HEBP), which is also called etidronic acid (4,5). This compound is applied in pool water disinfection because of its compatibility with calcium hypochlorite (hypochlorite tablets in swimming pools).…”

mentioning

confidence: 98%

Reduction of Hard-tissue Debris Accumulation during Rotary Root Canal Instrumentation by Etidronic Acid in a Sodium Hypochlorite Irrigant

Paqué

Rechenberg

Zehnder

2012

Journal of Endodontics

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Assessment of a gel‐type chelating preparation containing 1‐hydroxyethylidene‐1, 1‐bisphosphonate

Abstract: Under the conditions of this study, an HEBP gel appeared advantageous over currently available products.

Cited by 60 publications

References 19 publications

Root Canal Irrigants

Root Canal Irrigants

Longitudinal Co-site Optical Microscopy Study on the Chelating Ability of Etidronate and EDTA Using a Comparative Single-tooth Model

Reduction of Hard-tissue Debris Accumulation during Rotary Root Canal Instrumentation by Etidronic Acid in a Sodium Hypochlorite Irrigant

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