Assessment of Acute Phase Protein Serum hs-CRP Levels and its Role in Severity of Disease in Vitiligo Patients – A Hospital Based Case Control Study in M.Y. Hospital, Indore M.P.

Abstract

Introduction: Vitiligo an acquired pigmentary disorder of the skin and mucous membranes characterized by well circumscribed, depigmented macules and patches resulting from selective destruction of melanocytes. CRP is an acute phase protein secreted by the liver in response to several inflammatory cytokines such as IL6. Since inflammatory and immune factors plays a key role in the pathogenesis of vitiligo, we aimed to assess the relationship between the serum level of hs-CRP and pathogenesis and severity of vitiligo.