2015
DOI: 10.14283/jpad.2015.61
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Assessment of Age-Related Differences in Functional Capacity Using the Virtual Reality Functional Capacity Assessment Tool (Vrfcat)

Abstract: Clinical trials for primary prevention and early intervention in preclinical AD require measures of functional capacity with improved sensitivity to deficits in healthier, non-demented individuals. To this end, the Virtual Reality Functional Capacity Assessment Tool (VRFCAT) was developed as a direct performance-based assessment of functional capacity that is sensitive to changes in function across multiple populations. Using a realistic virtual reality environment, the VRFCAT assesses a subject’s ability to c… Show more

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Cited by 13 publications
(6 citation statements)
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“…The herein presented SH study provides a proof-of-concept for the feasibility of identifying, quantifying and assessing ADLs and differentiating known-groups via monitoring their performance. It is evident that new tools will be required to assess and evaluate clinically significant changes ( Atkins et al, 2015 ; Gold et al, 2018 ). The inclusion of people in preclinical stages of AD, constitutes an important step towards the advancement of digital biomarkers.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The herein presented SH study provides a proof-of-concept for the feasibility of identifying, quantifying and assessing ADLs and differentiating known-groups via monitoring their performance. It is evident that new tools will be required to assess and evaluate clinically significant changes ( Atkins et al, 2015 ; Gold et al, 2018 ). The inclusion of people in preclinical stages of AD, constitutes an important step towards the advancement of digital biomarkers.…”
Section: Discussionmentioning
confidence: 99%
“…These can vary from home based monitoring, personalized care, quality of life improvement, to independent living, observation and prediction of the actions of a person, caregiver burden reduction, intervention and disease progression monitoring, and also identification of emergency situations ( Amiribesheli and Bouchachia, 2018 ; Ault et al, 2020 ; Han et al, 2022 ; Miller et al, 2022 ). Furthermore, there is a growing interest in the use of using digital biomarkers assessing ADLs, as reliable proxies for screening participants for clinical trials or as secondary endpoints ( Atkins et al, 2015 ; Gold et al, 2018 ).…”
Section: Introductionmentioning
confidence: 99%
“…Additionally, some digital measures of functional capacity have shown sensitivity to age (e.g. Atkins et al, 2015 ), making them good candidates to assess functioning on an empirically driven, transdiagnostic basis in line with the U.S. National Institute of Mental Health initiated Research Domain Criteria (rDOC) project.…”
Section: Types Of Tools Used To Measure Functioning In Patients With ...mentioning
confidence: 99%
“…1 Categories of measures used to assess functioning in intervention studies with patients with schizophrenia. Examples of each category are given ( Hall, 1995 ; Morosini et al, 2000 ; Niendam et al, 2006 ; Auther et al, 2006 ; Hodgekins et al, 2015 ; Birchwood et al, 1990 ; Chopra et al, 2004 ; Herdman et al, 2011 ; Keefe et al, 2006 , Keefe et al, 2015 ; Patterson et al, 2001 ; Mausbach et al, 2007 ; Moore et al, 2015 ; Atkins et al, 2015 ; Ruse et al, 2014 ; Granholm et al, 2020; Jagesar et al, 2021b ). …”
Section: Introductionmentioning
confidence: 99%
“…The task was developed with grant support from the National Institute of Health (NIH) and the FDA to serve as a measure of functional improvement in clinical trials. Like the UPSA, it was originally standardized for use in schizophrenia, with subsequent studies demonstrating validity for assessment of functional capacity in older adults with cognitive impairment [24,25]. The VRFCAT was developed to measure four different functional abilities: meal preparation, using transportation, shopping, and managing currency.…”
Section: Introductionmentioning
confidence: 99%