Assessment of Antibacterial Activity of Five Endodontic Sealing Materials Against Enterococcus Faecalis

Abstract

Objective: Residual and recurrence infection can be prevented by a root canal sealer that possesses good antibacterial activity, which contributes to the success of endodontic therapy. This in-vitro study conducted to evaluate the antibacterial activity of five endodontic sealers (MTA fillapex, HS Mxima MTA, Endosequence BC sealer, BioRoot RCS, and AH plus) against Enterococcus faecalis using agar diffusion test. 
 Methods: Freshly mixed sealers were placed into prepared wells on agar plates. The diameter of the inhibition zone was measured after incubation for 24 hours. The data were analyzed statistically by ANOVA and LSD at a 0.05 significance.
 Results: All tested samples had an antimicrobial effect against Enterococcus faecalis after 24 hours. MTA fillapex had the greatest antimicrobial effect with an inhibition diameter of 12.77mm, followed by Endosequence BC. Finally, the weakest antimicrobial effect was related to the BioRoot RCS sealer with a mean zone of inhibition of 10.26mm.
 Conclusions: The root canal sealers showed different antimicrobial activity. However, MTA fillapex was the most effective sealer against the organism tested.