Assessment of antibacterial and antioxidant activity of aqueous crude flower, leaf, and bark extracts of Ethiopian
 Hibiscus rosa-sinensis
 Linn: geographical effects and Co
 2
 Res
 2
 /Glassy carbon electrode

Abate, Temesgen Assefa; Belay, Alebel Nibret

doi:10.1080/10942912.2022.2112598

Cited by 3 publications

(1 citation statement)

References 30 publications

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“…Ipomoea eriocarpa showed a higher amount of total polyphenols (0.98 ± 0.073 mg/g dry weight). Methnolic extract of Ipomoea species contain flowers ethanol extract contains highest amount of polyphenols which was in agreement with the current results [23]. Phytochemical screening of Ipomoea species also revealed the presence of tannins, saponins, flavonoids, triterpenes, phenols and alkaloids.…”

Section: Discussionsupporting

confidence: 92%

Antioxidant and Antimicrobial Activity of Cuscuta reflexa ROXB. and Few Members of Family Convolvulaceae

Noshad,

Ajaib,

Kiran

2023

CTO

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Antioxidant activity of 12 species, of which one was Cuscuta reflexa Roxb. which belongs to the family of Cuscutaceae as well as 11 of Convolvulaceae, collected from district Bhimber, Mirpur and Kotli were measured by using ABTS, DPPH and FRAP assay. The total phenol and flavonoid contents of the whole plant of all the selected species were investigated. Ipomoea eriocarpa showed a comparatively higher amount of total polyphenols (0.98 ± 0.073 mg/gdw). The maximum DPPH value was shown by Ipomoea carnea Jacq (5.6%) and the minimum value was shown by Convolvulus arvensis L. extracts (3.0 %). ABTS was the highest by Convolvulus prostrastus and the lowest by Ipomoea carnea. In FRAP assay, the highest value was 2.75 by Ipomoea hederacia and the lowest value was 0.31 by I. arachnosperma Welw. The antifungal and antibacterial activity of the methanolic extracts of the whole plant of all the selected species was carried out by using both bacterial and fungal strains. Two gram positive bacteria namely Staphylococcus aureus and Bacillus subtilis, two gram negative bacteria namely E. coli and Pseudomonas aeruginosa, two fungal strains of Aspergillus niger and Aspergillus oryzae were used to carry out antimicrobial activity. For the comparison of inhibition zones showed by plant extracts against bacterial and fungal strains. Erythromycin, tetracycline and cefoparazone were used as standard for bacterial strains. Moreover, fungivine and Terbinafine were used as standard antibiotics against fungal strains. Among fungal strains, the highest zone of inhibition was shown by Cuscuta reflexa Roxb. extract against Aspergillus niger, that is 5.55±0.3, while the lowest zone of inhibition, that is, 0.60±0.28mm was shown by Evolvulus alsinoides (L.) extract against Aspergillus oryzae. Plants from the Convolvulaceae family have had frequent traditional uses for different therapeutic purposes. Furthermore, all plants selected for this study showed strong antimicrobial, antifungal, and antioxidant activity. Their further detailed phytochemical studies can help to develop plant-based therapeutic agents

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Section: Discussionsupporting

confidence: 92%

Antioxidant and Antimicrobial Activity of Cuscuta reflexa ROXB. and Few Members of Family Convolvulaceae

Noshad,

Ajaib,

Kiran

2023

CTO

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Synthesis, characterization, and antibacterial activities of Cu-Ag bimetallic oxide nanocomposites using Eichhornia crassipes aqueous leaf extract

Belay,

Mihretu,

Getnet

2023

Journal of Experimental Nanoscience

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Epigallocatechin-3-Gallate attenuates lipopolysacharide-induced pneumonia via modification of inflammation, oxidative stress, apoptosis, and autophagy

Shen,

You,

et al. 2024

BMC Complement Med Ther

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Background Pneumonia, the acute inflammation of lung tissue, is multi-factorial in etiology. Hence, continuous studies are conducted to determine the mechanisms involved in the progression of the disease and subsequently suggest effective treatment. The present study attempted to evaluate the effects of Epigallocatechin-3-Gallate (EGCG), an herbal antioxidant, on inflammation, oxidative stress, apoptosis, and autophagy in a rat pneumonia model. Methods Forty male Wistar rats, 5 months old and 250–290 g were divided into four groups including control, EGCG, experimental pneumonia (i/p LPS injection, 1 mg/kg), and experimental pneumonia treated with EGCG (i/p, 15 mg/kg, 1 h before and 3 h after LPS instillation). Total cell number in the bronchoalveolar lavage fluid, inflammation (TNF-a, Il-6, IL-1β, and NO), oxidative stress (Nrf2, HO-1, SOD, CAT, GSH, GPX, MDA, and TAC), apoptosis (BCL-2, BAX, CASP-3 and CASP-9), and autophagy (mTOR, LC3, BECN1) were evaluated. Results The findings demonstrated that EGCG suppresses the LPS-induced activation of inflammatory pathways by a significant reduction of inflammatory markers (p-value < 0.001). In addition, the upregulation of BCL-2 and downregulation of BAX and caspases revealed that EGCG suppressed LPS-induced apoptosis. Furthermore, ECGC suppressed oxidative injury while promoting autophagy in rats with pneumonia (p-value < 0.05). Conclusion The current study revealed that EGCG could suppress inflammation, oxidative stress, apoptosis, and promote autophagy in experimental pneumonia models of rats suggesting promising therapeutical properties of this compound to be used in pneumonia management.

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Assessment of antibacterial and antioxidant activity of aqueous crude flower, leaf, and bark extracts of Ethiopian Hibiscus rosa-sinensis Linn: geographical effects and Co ₂ Res ₂ /Glassy carbon electrode

Cited by 3 publications

References 30 publications

Antioxidant and Antimicrobial Activity of Cuscuta reflexa ROXB. and Few Members of Family Convolvulaceae

Antioxidant and Antimicrobial Activity of Cuscuta reflexa ROXB. and Few Members of Family Convolvulaceae

Synthesis, characterization, and antibacterial activities of Cu-Ag bimetallic oxide nanocomposites using Eichhornia crassipes aqueous leaf extract

Epigallocatechin-3-Gallate attenuates lipopolysacharide-induced pneumonia via modification of inflammation, oxidative stress, apoptosis, and autophagy

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Assessment of antibacterial and antioxidant activity of aqueous crude flower, leaf, and bark extracts of Ethiopian Hibiscus rosa-sinensis Linn: geographical effects and Co 2 Res 2 /Glassy carbon electrode

Cited by 3 publications

References 30 publications

Antioxidant and Antimicrobial Activity of Cuscuta reflexa ROXB. and Few Members of Family Convolvulaceae

Antioxidant and Antimicrobial Activity of Cuscuta reflexa ROXB. and Few Members of Family Convolvulaceae

Synthesis, characterization, and antibacterial activities of Cu-Ag bimetallic oxide nanocomposites using Eichhornia crassipes aqueous leaf extract

Epigallocatechin-3-Gallate attenuates lipopolysacharide-induced pneumonia via modification of inflammation, oxidative stress, apoptosis, and autophagy

Contact Info

Product

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Assessment of antibacterial and antioxidant activity of aqueous crude flower, leaf, and bark extracts of Ethiopian Hibiscus rosa-sinensis Linn: geographical effects and Co ₂ Res ₂ /Glassy carbon electrode