Assessment of antibacterial efficacy of a biocompatible nanoparticle PC@AgNPs against Staphylococcus aureus

Ananda, A.P.; Manukumar, H.M.; Krishnamurthy, N. B.; Nagendra, Baku; Savitha, K. R.

doi:10.1016/j.micpath.2018.10.029

Cited by 37 publications

(20 citation statements)

References 37 publications

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“…As shown in Figure 4 a, AgNPs are spherical, ellipsoidal, or cylindrical, and their particle size range is 23–42 nm, and this is just like the morphology and granularity of AgNPs in previous research [ 49 ]. It conforms to nanoscience’s definition of nanoparticles with a particle size of 1–100 nm.…”

Section: Resultssupporting

confidence: 65%

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Investigation of Ultrasonic Treatment on Physicochemical, Structural and Morphological Properties of Sodium Alginate/AgNPs/Apple Polyphenol Films and Its Preservation Effect on Strawberry

Lan

Shama

et al. 2020

Polymers

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An antibacterial and anti-oxidation composite film was prepared by a casting method using sodium alginate (SA) and apple polyphenols (APPs) as the base material and glycerol as the plasticizer. Silver nanoparticles (AgNPs) were deposited by ultrasonic-assisted electrospray method. The degree of influence of the addition ratio of SA and AgNPs and different ultrasonic time on the mechanical properties, barrier properties, optical properties, and hydrophilicity of the composite film was explored. The composite films were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results showed that the SA: AgNPs ratio of 7:3 and the ultrasonic time for 30 min have the best comprehensive performance, and SA/AgNPs/APP films showed the lowest water vapor permeability value of 0.75 × 10−11 g/m·s·Pa. The composite film has good strength and softness, with tensile strength (TS) and elongation at break (E) at 23.94 MPa and 29.18%, respectively. SEM images showed that the surface of the composite film was smooth and the AgNPs’ distribution was uniform. The composite film showed broad antibacterial activity, and the antibacterial activity of Escherichia coli (92.01%) was higher than that of Staphylococcus aureus (91.26%). However, due to the addition of APP, its antioxidant activity can reach 98.39%, which has a synergistic effect on antibacterial activity. For strawberry as a model, the results showed that this composite film can prolong the shelf life of strawberries for about 8 days at 4 °C, effectively maintaining their storage quality. Compared with the commonly used PE(Polyethylene film) film on the market, it has a greater fresh-keeping effect and can be used as an active food packaging material.

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Section: Resultssupporting

confidence: 65%

“…It conforms to nanoscience’s definition of nanoparticles with a particle size of 1–100 nm. The high antibacterial activity of AgNPs is due to their large surface area, which can directly interact with microorganisms, while the antibacterial activity of AgNPs is related to particle size [ 49 ].…”

Section: Resultsmentioning

confidence: 99%

Investigation of Ultrasonic Treatment on Physicochemical, Structural and Morphological Properties of Sodium Alginate/AgNPs/Apple Polyphenol Films and Its Preservation Effect on Strawberry

Lan

Shama

et al. 2020

Polymers

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“…4 a). The other functional groups usually present at 1534 cm −1 , represented the stretch vibration of C=C for alkenes or C=O stretches for amides 37 , 38 . However, the percent transmittance peaks of chitosan at 1060 cm −1 and 1646 cm −1 indicated the C=O carbonyl stretching and N–H bending of primary amines, respectively.…”

Section: Resultsmentioning

confidence: 99%

Biosynthesis of silver nanoparticles for the fabrication of non cytotoxic and antibacterial metallic polymer based nanocomposite system

Raza

Ansari

Siddiqui

et al. 2021

Sci Rep

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Nanomaterials have significantly contributed in the field of nanomedicine as this subject matter has combined the usefulness of natural macromolecules with organic and inorganic nanomaterials. In this respect, various types of nanocomposites are increasingly being explored in order to discover an effective approach in controlling high morbidity and mortality rate that had triggered by the evolution and emergence of multidrug resistant microorganisms. Current research is focused towards the production of biogenic silver nanoparticles for the fabrication of antimicrobial metallic-polymer-based non-cytotoxic nanocomposite system. An ecofriendly approach was adapted for the production of silver nanoparticles using fungal biomass (Aspergillus fumigatus KIBGE-IB33). The biologically synthesized nanoparticles were further layered with a biodegradable macromolecule (chitosan) to improve and augment the properties of the developed nanocomposite system. Both nanostructures were characterized using different spectrographic analyses including UV–visible and scanning electron microscopy, energy dispersive X-ray analysis, dynamic light scattering, and Fourier transform infrared spectroscopic technique. The biologically mediated approach adapted in this study resulted in the formation of highly dispersed silver nanoparticles that exhibited an average nano size and zeta potential value of 05 nm (77.0%) and − 22.1 mV, respectively with a polydispersity index of 0.4. Correspondingly, fabricated silver–chitosan nanocomposites revealed a size of 941 nm with a zeta potential and polydispersity index of + 63.2 mV and 0.57, respectively. The successful capping of chitosan on silver nanoparticles prevented the agglomeration of nanomaterial and also facilitated the stabilization of the nano system. Both nanoscopic entities exhibited antimicrobial potential against some pathogenic bacterial species but did not displayed any antifungal activity. The lowest minimal inhibitory concentration of nanocomposite system (1.56 µg ml−1) was noticed against Enterococcus faecalis ATCC 29212. Fractional inhibitory concentration index of the developed nanocomposite system confirmed its improved synergistic behavior against various bacterial species with no cytotoxic effect on NIH/3T3 cell lines. Both nanostructures, developed in the present study, could be utilized in the form of nanomedicines or nanocarrier system after some quantifiable trials as both of them are nonhazardous and have substantial antibacterial properties.

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“…Further details on the physic-chemical and biological attributes of P. cordifolia-assisted silver nanoparticles were reported by the present authors [24]. It was considered necessary to obtain extra information to substantiate the potential of the nanoparticle preparation in biomedical, pharmaceutical and environmental and the data obtained are presented in this article.…”

Section: Introductionmentioning

confidence: 69%

“…The synthesized PC@AgNPs was confirmed by the absorption spectrum obtained using Shimadzu UV-visible spectrometer. The PC@AgNPs was detail characterized by FTIR, SEM, TEM, EDX, DLS and XRD in a previous report and same material was used for further studies [24].…”

Section: Synthesis and Characterization Of Pc@agnpsmentioning

confidence: 99%

Biogenic synthesis of silver nanoparticles using Priva cordifolia leaf extract (PC@AgNPs) a potent antioxidant, antibacterial and catalytic activity

et al. 2019

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A nanoparticle preparation (PC@AgNPs), synthesized biogenically using Priva cordifolia leaf extract was found to possess quenching property of stable DPPH and ABTS in dose dependent manner. The PC@AgNPs showed well-established physicochemical stability with respect to temperature, P H and salinity. It showed a broad bactericidal effect against 10 pathogenic bacteria, notably Staphylococcus aureus, Escherichia coli, Shigella flexneri and Vibrio parahaemolyticus. Its non-toxicity up to 500 µg mL −1 concentration to peripheral blood mononuclear cells was recorded. However, its toxic effect against human lung carcinoma cells and human breast adenocarcinoma cell lines at a dose of 500 and 300 µg mL −1 respectively was clearly evident. The catalytic efficiency of PC@AgNPs was demonstrated in methylene blue and methyl orange dye degradation. The studies have suggested possible applications of PC@AgNPs in future biomedical, pharmaceutical, and environmental applications.

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Assessment of antibacterial efficacy of a biocompatible nanoparticle PC@AgNPs against Staphylococcus aureus

Cited by 37 publications

References 37 publications

Investigation of Ultrasonic Treatment on Physicochemical, Structural and Morphological Properties of Sodium Alginate/AgNPs/Apple Polyphenol Films and Its Preservation Effect on Strawberry

Investigation of Ultrasonic Treatment on Physicochemical, Structural and Morphological Properties of Sodium Alginate/AgNPs/Apple Polyphenol Films and Its Preservation Effect on Strawberry

Biosynthesis of silver nanoparticles for the fabrication of non cytotoxic and antibacterial metallic polymer based nanocomposite system

Biogenic synthesis of silver nanoparticles using Priva cordifolia leaf extract (PC@AgNPs) a potent antioxidant, antibacterial and catalytic activity

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