Assessment of antifungal activity of herbal and conventional toothpastes against clinical isolates of Candida albicans

Abstract

In the present study, it has been demonstrated that toothpaste containing both herbal extracts and sodium fluoride as active ingredients are more effective in control of C. albicans, while toothpaste that containing monofluorophosphate as an active ingredient is less effective against C. albicans. Some herbal toothpaste formulations studied in our experiments, appear to be equally effective as the fluoride dental formulations and it can be used as an alternative to conventional formulations for individuals who have an interest in naturally-based products. Our results may provide invaluable information for dental professionals.

Antimicrobial Efficacy of Ten Commercially Available Herbal Dentifrices against Specific Oral Microflora – In Vitro Study

“…Likewise, study by Adwan G et al, [27] reported that Dabur Meswak herbal toothpaste exhibited antifungal activity against C. albicans. On the other hand, in this study, Dabur Meswak (DM) except for S. pyogenes (40 mm) formed significantly smaller zones of inhibition against the specific oral microflora as compared to other tested herbal dentifrices.…”

Essential Oils of Lamiaceae Family Plants as Antifungals

“…Additionally, in some toothpastes are essential oils, e.g., in "Parodontax ® " occurs Salvia officinalis oil, Mentha piperita oil, and Mentha arvensis oil; in "Lacalut Active Herbal" is Mentha arvensis oil, Thymus vulgaris oil, and Salvia officinalis oil, while in "Signal Family Herbal Fresh" are oils from Mentha piperita and Salvia officinalis [194]. Literature data confirm a strong antifungal effect against C. albicans and anti-inflammatory activity of "Parodontax" toothpaste [195,196]. Besides toothpastes, also some medicines used to rinse the oral cavity or throat contain a large number of essential oils.…”

Inhibitory effects of medical plants on the Candida albicans and bacterial growth in the oral cavity

“…These antimicrobial agents include metal salts, phenols, herbal extracts, enzymes, essential oils, and bisbiguanides (Stamm, 2007;Yiğit et al, 2008). Toothpaste has been formulated to contain chemotherapeutic agents to improve the oral health, to produce inhibitory action on plaque formation as well as bacteria and Candida colonization (Gardiner et al, 2008;Yiğit et al, 2008;Sadeghi and Assar, 2009;Adwan et al, 2012). However, there is a different approach to the oral hygiene.…”