Assessment of antimicrobial potential of 10% ginger extract against Streptococcus mutans, Candida albicans, and Enterococcus faecalis: An in vitro study

Giriraju, Anjan; Yunus, G Y

doi:10.4103/0970-9290.118356

Cited by 52 publications

(26 citation statements)

References 9 publications

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“…About the extract of ginger in the study by Giriraju and Yunus [31] using the agar disc diffusion test, a 10% ethanolic extract exhibited good antimicrobial potential against Streptococcus mutans, E. faecalis, and C. albicans, with inhibition zones of 8, 14, and 11 mm, respectively. However, the authors concluded that further studies are necessary to evaluate the practical and economic feasibility of this extract and to recommend its use in clinical practice.…”

Section: Discussionmentioning

confidence: 97%

Antibacterial Activity of Rosmarinus officinalis, Zingiber officinale, Citrus aurantium bergamia, and Copaifera officinalis Alone and in Combination with Calcium Hydroxide against Enterococcus faecalis

Silva

Alves

Silva

et al. 2019

BioMed Research International

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is study aimed to evaluate the efficacy of different concentrations of essential oils combined with calcium hydroxide against Enterococcus faecalis. irteen experimental groups were formed: NC (negative control); PC (positive control); GC (growth control); SC (sterilization control); RO (Rosmarinus officinalis); ROH (calcium hydroxide + RO); ZO (Zingiber officinale); ZOH (calcium hydroxide + ZO); AB (Citrus aurantium bergamia); ABH (calcium hydroxide + AB); CO (Copaifera officinalis); COH (calcium hydroxide + CO); DWH (calcium hydroxide and distilled water). After reconstitution of the E. faecalis strain, microdilution testing was performed to define the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). e data were tabulated in an Excel spreadsheet, and the MIC and MBC were calculated in accordance with the Bacteriological Analytical Handbook. MICs in the range of 0 to 100 mg/ml were only observed in the ROH group. e RO, ROH, AB, ZO, and ZOH presented absolute data for MBC. Bacterial growth was detected in the DWH group at all concentrations tested. e combination of the essential oils tested here with calcium hydroxide appears promising as an intracanal medication in endodontic treatment because of its effectiveness against Enterococcus faecalis. Essential oils are important in endodontic therapy since calcium hydroxide, the gold standard intracanal medication, is not effective against E. faecalis.

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Section: Discussionmentioning

confidence: 97%

Antibacterial Activity of Rosmarinus officinalis, Zingiber officinale, Citrus aurantium bergamia, and Copaifera officinalis Alone and in Combination with Calcium Hydroxide against Enterococcus faecalis

Silva

Alves

Silva

et al. 2019

BioMed Research International

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“…[13] A study that examined the antimicrobial properties of ginger extract 10% indicated that minimum inhibitory concentration was 2.5% in the ethanolic extract of ginger and inhibitory properties of this plant on bacteria were confirmed; as a result, this plant can be used as an antifungal compound. [14] In a review article that examined active compounds of ginger for the treatment of various diseases, the results showed that the rhizome of the plant has appropriate antibacterial and antifungal properties. [4] Studies show that substances such as [10]-gingerol and [12]-gingerol can play an important role in antimicrobial properties of ginger rhizome extract.…”

Section: Discussionmentioning

confidence: 99%

The effect of vaginal cream containing ginger in users of clotrimazole vaginal cream on vaginal candidiasis

Shabanian

Khalili

Lorigooini

et al. 2017

J Adv Pharm Technol Res

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“…[ [29][30][31] However, it comes in disagreement with Gull et al (2012) [32] who found that the total ethanolic ginger extract possessed poor antimicrobial eff ect. This might be attributed to the diff erence in susceptibility of the tested extract against diff erent types of microorganisms, since the extract was tested against eight types of clinical bacterial isolates, other than E. faecalis.…”

Section: Discussionmentioning

confidence: 99%

“…All plants extracts used in the present study have been found to be less eff ective against E. faecalis than (NaOCl 5.25%), this might be attributed to the high concentration of NaOCl in comparison to other studies that used (NaOCl 2%)as a positive control. [24,26,30,42] …”

Section: Discussionmentioning

confidence: 99%

Evaluation of antimicrobial efficacy of four medicinal plants extracts used as root canal irrigant on Enterococcus faecalis: An in-vitro study

Radwan¹,

Randa²,

Hend³

et al. 2015

IDJAR

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Aim: Evaluation and comparison of the antimicrobial effi ciency of the medicinal plant extracts, when used as root canal irrigants, on single species of Enterococcus faecalis. Materials and Methods: A comparative bioactivity-guided fractionation of four medicinal plants was carried out using solvents with diff erent polarities (ethanol, hexane, ethyl acetate, butanol, and water). The organism was freshly inoculated in brain-heart infusion broth for 24 h prior to the test, and the inoculum was standardized. Cultures were spread over the surface of the plate, and wells were punched out in every plate. Each well was inoculated by each extract and incubated for 24 h and the zone of inhibition around each well was recorded. A total of 50 extracted human single rooted teeth were disinfected decapitated and prepared, then divided into six groups: Group I: Neem leaf extract, Group II: Ginger extract, Group III: Miswak extract, Group IV: Lemon solution, Group V: NaOCl 5.25% (+ve control), and Group IV: Saline (−ve control). Each root canal was completely fi lled with bacterial suspension and incubated at 37°C for 24 h, then completely fi lled with one of the medicinal plants extract according to each group. Root specimens were then incubated for 24 h at 37°C. The root canals were sampled, and the samples were contained and incubated for 24 h at 37°C. The colony forming units (CFU) were calculated. Data presented as mean and standard deviation values. One-way analysis of variance (ANOVA)was used for comparisons between more than two groups. Tukey's post-hoc test was used for pair-wise comparison between the groups when ANOVA test was signifi cant. Results: NaOCl 5.25% showed signifi cantly less CFU/ml count, when compared with all tested plant extracts (P < 0.001). This was followed by fresh lemon solution which showed signifi cantly less CFU/ml count when compared with all of the other tested plant extracts. Butanol fraction of ginger showed signifi cantly less CFU/ml count than ethyl acetate fraction of miswak and neem. Conclusions: Medicinal herbs may off er a new source of antibacterial agents for use; medicinal plants are natural antimicrobial agents and might be used in the development of a promising irrigants, which might be safer than other chemical compounds used in the endodontic treatment process.

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Assessment of antimicrobial potential of 10% ginger extract against Streptococcus mutans, Candida albicans, and Enterococcus faecalis: An in vitro study

Abstract: 10% ethanolic ginger extract was found to possess antimicrobial potential against all the three pathogens used in the study.

Cited by 52 publications

References 9 publications

Antibacterial Activity of Rosmarinus officinalis, Zingiber officinale, Citrus aurantium bergamia, and Copaifera officinalis Alone and in Combination with Calcium Hydroxide against Enterococcus faecalis

Antibacterial Activity of Rosmarinus officinalis, Zingiber officinale, Citrus aurantium bergamia, and Copaifera officinalis Alone and in Combination with Calcium Hydroxide against Enterococcus faecalis

The effect of vaginal cream containing ginger in users of clotrimazole vaginal cream on vaginal candidiasis

Evaluation of antimicrobial efficacy of four medicinal plants extracts used as root canal irrigant on Enterococcus faecalis: An in-vitro study

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