Assessment of antioxidant activities of HeukHarang a novel Korean Lectuca sativa L.

Jang, Seo Woo; Kim, Yong‐Dae; LEE, Songmi; Yim, Soon‐Ho

doi:10.1590/fst.06522

Cited by 3 publications

(1 citation statement)

References 36 publications

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“…The diversity of free radicals produced in the body necessitates multiple antioxidant assays to measure radical scavenging ability (Liang & Kitts, 2014). Various antioxidant activity assays, including DPPH radical scavenging activity and ABTS radical scavenging activity, are used to analyze antioxidant activity of food and food materials (Jang et al, 2022). In addition, the antioxidant activity of the sample can be expressed in various ways.…”

Section: Introductionmentioning

confidence: 99%

Comparison of antioxidant activities expressed as equivalents of standard antioxidant

HWANG

LEE

2023

Food Sci. Technol

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The quantitative antioxidant activity of foods is expressed as the equivalent weight of the authentic standard compounds with antioxidant function. Even in the same food sample, antioxidant activity is defined differently depending on the standard antioxidant compounds, making it difficult to compare them. Antioxidant activity was measured by DPPH radical and ABTS radical scavenging assay using Trolox, ascorbic acid, catechin, and gallic acid as standard antioxidant compounds. The relationship between the antioxidant activity and the standard was used to convert the antioxidant activity expressed as the equivalent of a specific antioxidant standard to the equivalent of another antioxidant standard. To verify the converted antioxidant activity, the antioxidant activity of apples was analyzed with several antioxidant standards and compared with the antioxidant activity converted with other standard compounds. As a result of comparing the antioxidant activity measured using various antioxidant standards and the converted antioxidant activity of apples, it was confirmed that there was no difference. The results of this study show that antioxidant activity expressed as a specific antioxidant standard compound can be accurately converted into the equivalent of another standard antioxidant compound.

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Section: Introductionmentioning

confidence: 99%

Comparison of antioxidant activities expressed as equivalents of standard antioxidant

HWANG

LEE

2023

Food Sci. Technol

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The Antimelanogenic Activity of the Extract of Heukharang Lettuce (Lactuca sativa L.) Leaf

Ko,

Shon,

Lim

et al. 2024

Journal of Food Biochemistry

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Heukharang (Lactuca sativa L.), the artificially developed lettuce cultivar for enhancement of lactucin content, exhibits antioxidant activities and sleep-promoting effects. However, potential of Heukharang as a raw material for the skin-whitening agent has not been investigated yet. This study evaluated the effects of Heukharang extract (HHE) on α-melanocyte-stimulating hormone (α-MSH)-induced melanogenesis in vitro and in vivo models. Our findings revealed that HHE (25–100 μg/mL) effectively inhibited α-MSH-induced melanin synthesis in both 2D and 3D cell culture environments without compromising the viability of the B16F10 murine melanoma cell line. Furthermore, HHE suppressed intracellular tyrosinase activity, along with both gene and protein expression of tyrosinase (TYR) and tyrosinase-related protein (TRP)-1 and TRP-2. HHE downregulated the mRNA level of microphthalmia-associated transcription factor (MITF) and the phosphorylation of cAMP response element-binding (CREB) protein. The antimelanogenic activity of HHE (50 and 100 μg/mL) was also confirmed using a zebrafish embryo model, highlighting its efficacy in inhibiting α-MSH-induced melanogenesis through the downregulating CREB/MITF/TYR signaling pathways. Moreover, our study demonstrated that a corresponding amount of lactucin (5–20 μM) to the HHE inhibited and regulated melanogenesis. These results collectively suggest that HHE, enriched with lactucin, holds promise as a potential skin-whitening agent for nutricosmetic industries.

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Sleep-potentiating Effects of Passiflora incarnata and ‘Heukharang’, a Novel Korean Lactuca sativa, on Pentobarbital-induced Sleep in Mice

Ortiz,

Oh,

Kwon

et al. 2023

nps

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Assessment of antioxidant activities of HeukHarang a novel Korean Lectuca sativa L.

Cited by 3 publications

References 36 publications

Comparison of antioxidant activities expressed as equivalents of standard antioxidant

Comparison of antioxidant activities expressed as equivalents of standard antioxidant

The Antimelanogenic Activity of the Extract of Heukharang Lettuce (Lactuca sativa L.) Leaf

Sleep-potentiating Effects of Passiflora incarnata and ‘Heukharang’, a Novel Korean Lactuca sativa, on Pentobarbital-induced Sleep in Mice

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