Assessment of antioxidant and antimicrobial activities of Crambe spp. during vegetation

Abstract

Background. The search for new plant raw material as a potential source of antioxidants is still ongoing. This study aimed to evaluate the antioxidant and antimicrobial capacity of the plant raw material of Crambe spp. during vegetation. Materials and methods. The free radical scavenging activity and molybdenum reducing power of the extracts were used to determine antioxidant activity. The quantification of polyphenol compounds was conducted with Folin-Ciocalteu reagent. Flavonoids and phenolic acids were also determined. The disc diffusion method was used to determine antimicrobial activity. Results. It was determined that the free radical scavenging activity, assessed using the DPPH-method, was 4.38-8.20 mg TE/g DW, the molybdenum reducing power of the extracts was 40.07-129.12 mg TE/g DW, total polyphenol content was 20.24-70.88 mg GAE/g DW, total flavonoid content was 5.73-29.92 mg QE/g DW, and phenolic acid content was 3.00-10.63 mg CAE/g DW. Antimicrobial activity depended on the stage of growth and the part of the plant used. Conclusion. Crambe spp. possess the antioxidant and antimicrobial potential to mean that they could be used in pharmaceutical studies and the food industry.

Phytochemical Composition, Bioavailability and Pharmacokinetics of Scorzonera undulata Methanolic Extracts: Antioxidant, Anticancer, and Apoptotic Effects on MCF7 Cells

“…undulata, particularly from the Ha'il region, exert synergistic anti-tumoral effects that are worth further exploration in counteracting cancer. Similar anticancer and health promotion effects have been previously reported by these compounds from Scorzonera species and others (Ajebli et al, 2021;Jedli et al, 2022;Vergun et al, 2018;Zammel et al, 2022). These effects were also confirmed by bioavailability and pharmacokinetic analyses.…”

“…In vitro evaluation of anticancer activity by MTT assay was carried out using the MCF7 breast cancer cell line (Vergun et al, 2018). Cells were grown in 96-well plates using Roswell Park Memorial Institute (RPMI) medium containing 7% fetal bovine serum (FBS) at 37°C, 100% relative humidity, 5% CO 2 and 95% air conditioning.…”

Evaluation of the Turkish warty cabbage (Bunias orientalis) plant’s roots prospects as a food raw material

“…Шығыс майракебісі туысына жататын өсімдіктердің бойында биоактивті заттардың жинақталуын зерттеуге бағытталған еңбектерде олардың жоғары антиоксидантты және бос радикалдарды бейтараптайтын қасиеттері көрсетіледі, демек атаулы шикізат түрін дәрілік мақсатта пайдалануға толық негіздеме бар [24][25][26].…”