Assessment of Antioxidant and Antimicrobial
Compounds of Volatiles from Leaves,
Stems and Flowers of Olives

Naija, Dhouha Saidana; Gueddes, Samia Ben Mansour; Flamini, Guido; Khiareddine, Hayfa Jabnoun; Remadi, Mejda Daami; Mariem, Fathi Ben; Ghariani, Wafa; Braham, Mohamed

doi:10.15244/pjoes/121514

Cited by 4 publications

(3 citation statements)

References 30 publications

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“…In addition, the abundance of these triterpenes in the adsorbates increased compared with CL (global control), from around 30% for uvaol in CL to 50% in SS adsorbate (SS ads). The enrichment of this kind of pentacyclic triterpenes is significant considering their potential anti-inflammatory, antioxidant, and cardioprotective bioactivities, among others [12,[61][62][63]. α-tocopherol is another compound of interest not only for its recognized antioxidant capacity but also for its ability to transport target compounds with bioactive potential through neuronal cells [64].…”

Section: Figurementioning

confidence: 99%

Neuroprotective Effect of Terpenoids Recovered from Olive Oil By-Products

Montenegro

Álvarez‐Rivera

Sánchez-Martínez

et al. 2021

Foods

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The neuroprotective potential of 32 natural extracts obtained from olive oil by-products was investigated. The online coupling of supercritical fluid extraction (SFE) and dynamic adsorption/desorption allowed the selective enrichment of olive leaves extracts in different terpenoids’ families. Seven commercial adsorbents based on silica gel, zeolite, aluminum oxide, and sea sand were used with SFE at three different extraction times to evaluate their selectivity towards different terpene families. Collected fractions were analyzed by gas chromatography coupled to quadrupole-time-of-flight mass spectrometry (GC-QTOF-MS) to quantify the recoveries of monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), and triterpenes (C30). A systematic analysis of the neuroprotective activity of the natural extracts was then carried out. Thus, a set of in vitro bioactivity assays including enzymatic (acetylcholinesterase (AChE), butyrylcholinesterase (BChE)), and anti-inflammatory (lipoxidase (LOX)), as well as antioxidant (ABTS), and reactive oxygen and nitrogen species (ROS and RNS, respectively) activity tests were applied to screen for the neuroprotective potential of these extracts. Statistical analysis showed that olive leaves adsorbates from SS exhibited the highest biological activity potential in terms of neuroprotective effect. Blood–brain barrier permeation and cytotoxicity in HK-2 cells and human THP-1 monocytes were studied for the selected olive leaves fraction corroborating its potential.

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Section: Figurementioning

confidence: 99%

Neuroprotective Effect of Terpenoids Recovered from Olive Oil By-Products

Montenegro

Álvarez‐Rivera

Sánchez-Martínez

et al. 2021

Foods

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“…Numerous publications about the study of olive extracts have been published recently, albeit these studies focus mostly on the volatile components because of their antioxidant activity (Naija et al, 2021). Beyond the leaves and the oil, a thorough evaluation of the various extraction techniques for the many olive tree materials was lacking.…”

Section: State Of Artmentioning

confidence: 99%

Bioactive chemlali olive derivatives and compounds useful for pharmaceutical purposes: A review

Ksibi

2023

ijpbp

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Several articles in the literature deal with and analyze components extracted from the olive tree, but these researches are mainly focused on the quality of olive oil and more precisely its volatile components, often related to their antioxidant properties, which denies other derivatives of the olive tree that are traditional sources of several healing broths. A thorough comparison of the richness of the different derivatives as well as the methods of extraction and identification will help to provide a useful decision-making tool. Olive tree derivatives were extracted in different ways to better understand the chemical composition of the Chemlali olive tree variety as well as to evaluate the efficiency of advanced extraction procedures. A comparison through the IC50 of the Chemlali variety with other olive cultivars was performed. It shows the richness of this variety in polyphenols. In addition, we present here a qualitative and quantitative table of basic chemicals for pharmacological use derived from olive oil, leaf, and bark that have been previously described in the literature. Diverse types and concentrations of phenolic compounds-an important class of natural antioxidants-can be found in different components of olives, including leaves, fruit, pits, seeds, bark, and paste. However, comprehensive studies are deficient in comparing the quantities extracted from these different sources. Indeed, this review attempt shows the diversity of Chemlali through the use of highvalue-added molecules (VAT), which can be categorized as diterpenes such as tyrosol and phytol, triterpenes such as squalene, as well as cinnamates.

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“…Many phytochemicals are known firstly for their powerful antioxidant capacity to cope thermal, drought and oxidative stress, secondly for their antifungal activity against pathogenic fungi for several species [18-25, 52, 53]. In this context, Saidana et al [53] suggested that volatiles might be an eventual source of alternative antimicrobial and antioxidant agents interesting for potential use in the biological control. These results encourage us to promote them in the agronomic sector.…”

Section: Principal Component Analysis (Pca)mentioning

confidence: 99%