Assessment of anxiety, depression, and distress in breast cancer patients: A comparison among different phases of illness

Botto, Rossana; Leonardis, Brigitta De; Salussolia, Annarita; Nardo, Cristina Di; Ala, Ada; Torta, Riccardo; Stanizzo, Maria Rosa

doi:10.1080/07399332.2022.2078325

Cited by 4 publications

(7 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most important finding is that almost twice as many patients reported significant PTSS during the pandemic COVID-19 than the comparable patients studied during the same period one year earlier. However, it should also be considered that changes in the degree of psychological distress were described depending on the time of assessment [ 13 ], which is due to the different situations usually faced during the different phases of the disease [ 2 , 14 ].…”

Section: Discussionmentioning

confidence: 99%

Psychological Distress in Breast Cancer Patients during the Italian COVID-19 Pandemic

Stanizzo

Castelli

Nardo

et al. 2022

IJERPH

Self Cite

View full text Add to dashboard Cite

Background. The emergency caused by the SARS-CoV-2 pandemic exacerbated psychological distress. Our aim was to investigate the impact of breast cancer on patients’ lives during the Italian lockdown. Methods. Sixty-five female breast cancer patients were studied, assessing the level of psychological distress with the Hospital Anxiety and Depression Scale (HADS) and the impact of the cancer diagnosis (Impact of Event Scale-Revised—IES—R). In addition, we compared these data with a matched group of breast cancer patients enrolled in 2019. Results. Patients enrolled in 2020 had statistically higher levels of anxious symptomatology and higher levels of traumatic symptomatology due to the cancer diagnosis. A mediation analysis was performed to determine how the experience of distress due to COVID-19 negatively impacted the level of anxiety and amplified the impact of the diagnosis with a significant increase in traumatic symptoms. Conclusions. Considering the vulnerability of these patients and the serious and novel situation that the healthcare system is currently facing, we would like to point out the importance of structured and organised psychological support for these patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Psychological Distress in Breast Cancer Patients during the Italian COVID-19 Pandemic

Stanizzo

Castelli

Nardo

et al. 2022

IJERPH

Self Cite

View full text Add to dashboard Cite

show abstract

“…In response to chronic stress, the physiologic mechanisms involve the neuroendocrine pathways constituting the SNS and HPA axis [3,4] . Both mechanisms are initiated by releasing several neurotransmitters and hormones that affluence behavioural and biochemical changes [18] .…”

Section: Hypothalamic-pituitary-adrenal Axis In Response To Chronic S...mentioning

confidence: 99%

“…Almost two million cases of BC were diagnosed in last years, according to the World Health Organization (WHO) [2] . Both non-pharmacological and pharmacological treat-ments of BC can result in adverse side-effects at distinct levels, such as physical function, metabolic, cardiorespiratory and psychological [3,4] . These consequences may be associated with an interaction between pharmacological therapies and physiopathological and psychological conditions of each woman at the moment of diagnosis.…”

Section: Introductionmentioning

confidence: 99%

“…Although research is still limited, the dysregulation of HPA axis and SNS, depression and anxiety have been reported in BC patients and survivors [5] . Studies show that almost 50% of BC patients experienced depression and/ or anxiety during cancer treatments [4,6] and approximately 25% of women have clinically important levels of emotional distress up to 12 months after treatment [5] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cortisol Response in Breast Cancer: The Role of Physical Activity and Exercise

Marinho

Rocha-Rodrigues²

2022

j. of Endocrinol. res.

View full text Add to dashboard Cite

Chronic stress is a consistent sense of feeling pressured and overwhelmedfor a long period of time and it has been defined as a maladaptive state thatis associated with altered hypothalamic pituitary adrenal (HPA) axis. Thehyperactivity of the HPA axis is commonly assessed by cortisol levels.Physical activity (PA) and exercise have been demonstrated to regulatecortisol patterns in different healthy study populations, but also in BCpatients and survivors. The PA and exercise are related but have distinctconcepts that are commonly misused. Nowadays, the regular practice of PAand exercise has been widely recognized as one main strategy to managechronic stress and its related markers, like cortisol, remains elusive. In thepresent review, the authors focused on the evidence of the PA and exerciseon cortisol patterns of BC patients and survivors.

show abstract

“…Women may experience symptoms of anxiety and depression due to the burden of treatment, and the uncertainties and fears about recovery. 7,8 In the survivorship phase, the long-term side effects of cancer treatments may contribute to reduced quality of life, increased mental distress, and psychological morbidities such as anxiety and depression. [9][10][11][12] In all phases of the disease, women with pre-existing mental health problems are at risk for experiencing physical and mental impairments throughout the course of breast cancer.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of group therapy to reduce mental distress in women with non‐metastatic breast cancer: A systematic review and meta‐analysis of randomized controlled trials

Rosendahl

Gawlytta

Ressel³

et al. 2023

Psycho-Oncology

View full text Add to dashboard Cite

Objective: Group treatments have proven to be effective for many mental disorders and showed beneficial effects in patients with medical illness. Aim of this systematic review and meta-analysis is to summarize the efficacy of group therapy for women with non-metastatic breast cancer. Methods:We included studies comparing group therapy for women with nonmetastatic breast cancer to non-active control groups, active control conditions, and individual psychotherapy. The primary outcome was mental distress, secondary outcomes were quality of life, coping, existential outcomes, fatigue, pain, and side effects. A comprehensive search was conducted in Medline, Web of Science, CENTRAL, PsycINFO, and DARE complemented by a manual search.Random-effects meta-analyses were run separately for different types of control groups.Results: Thirty-seven studies (5902 patients) were included. Small effects on mental distress in favor of group treatment were found (non-active control groups: n = 19, g = 0.42, 95% CI [0.29; 0.56], I 2 = 61.6%; active control conditions: n = 6, g = 0.20, 95% CI [0.06; 0.35], I 2 = 0%). Cognitive-behavioral therapy (CBT) and third wave CBT group approaches proved to be most effective. Group treatments also showed beneficial effects on secondary outcomes, with most profound evidence on quality of life and coping.Conclusions: Results suggest that group interventions have the potential to reduce mental distress in women facing breast cancer. In the light of the considerable heterogeneity of most study effects, there is a need for more rigorous studies to strengthen the promising evidence and for trials examining the impact of patient and intervention characteristics on outcomes.Registration: PROSPERO international prospective register of systematic reviews, CRD42020184357.

show abstract

Assessment of anxiety, depression, and distress in breast cancer patients: A comparison among different phases of illness

Cited by 4 publications

References 26 publications

Psychological Distress in Breast Cancer Patients during the Italian COVID-19 Pandemic

Psychological Distress in Breast Cancer Patients during the Italian COVID-19 Pandemic

Cortisol Response in Breast Cancer: The Role of Physical Activity and Exercise

Efficacy of group therapy to reduce mental distress in women with non‐metastatic breast cancer: A systematic review and meta‐analysis of randomized controlled trials

Contact Info

Product

Resources

About