The paper presents the level and spatial distribution of total chloride, arsenic and aluminum contents, and that of microbiological parameters (coliform bacteria, E. coli bacteria, intestinal enterococci) from water wells situated in the Seini area, both on the surface and in depth, using the geostatistical module of ArcGIS. The relations between the levels of microorganisms and the concentrations of chemical parameters (total chlorides, As and Al) were established using Table Curve program for generating 3D mathematical models.