Assessment of autonomic tone over a 24-hour period in patients with congestive heart failure: Relation betweeen mean heart rate and measures of heart rate variability

Panina, Gaia; Khot, Umesh N.; Nunziata, Enrico; Cody, Robert J.; Binkley, Philip F.

doi:10.1016/0002-8703(95)90325-9

Cited by 55 publications

(30 citation statements)

References 28 publications

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“…20,21 Thus, the patients with reduced circadian rhythmicity of HRV may have impaired autonomic nervous function such as diabetic neuropathy, 12 prior myocardial infarction 13,14 or congestive heart failure. 15,16 Previous studies demonstrated that patients with NSVT also have reduced circadian variation of HRV; 7,10 however, we noted that some patients with NSVT have a preserved circadian rhythm. In the present study, the amplitude of both HF and LF/HF was significantly higher in the positive circadian groups than in the negative circadian groups, and the acrophase was shifted to the daytime in the HF-negative group and to the nighttime in the LF/HF-negative group.…”

Section: Discussionmentioning

confidence: 63%

Role of Circadian Rhythmicity in the Heart Rate Variability Preceding Non-Sustained Ventricular Tachycardia

et al. 1998

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Section: Discussionmentioning

confidence: 63%

Role of Circadian Rhythmicity in the Heart Rate Variability Preceding Non-Sustained Ventricular Tachycardia

et al. 1998

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“…15 Increased HR and plasma catecholamines correlate with reduced HR variability and poor prognosis. 16 Thus, initially our data would indicate that less use of beta-blocker therapy in the subgroup of patients with high HR and low SBP may explain why those patients tended to have worse outcomes. However, the covariate-adjusted hazard ratio suggests that hemodynamic profile predicts a significant proportion of variance beyond that accounted for by the individual covariates such as beta-blocker use or ischemic etiology.…”

Section: Clinical Hemodynamic Profiles In Heart Failurementioning

confidence: 76%

Initial Heart Rate and Systolic Blood Pressure Predict Outcomes in Chronic Heart Failure Patients who are Evaluated for Cardiac Transplant

Aranda¹,

McIntyre²,

Klodell³

et al. 2007

Clinical Cardiology

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SummaryBackground: Heart rate (HR) and systolic blood pressure (SBP) are currently not considered among common clinical indicators of prognosis in patients referred for heart transplant (Htx). We sought to determine whether an initial hemodynamic profile of HR and SBP could be used to predict outcomes in chronic heart failure patients evaluated for Htx.Methods: We analyzed the medical records of patients evaluated for Htx and obtained demographic and clinical data collected at the initial transplant clinic visit or inpatient encounter. We assigned patients to groups based on their HR and SBP. Groups were compared after follow-up for differences in freedom from death or Htx.Results: From 1999 to 2003, 400 consecutive patients were considered by the local Htx medical review board. The median duration of follow-up was 26 months (interquartile range 1 to 45 months). Patients with initial HR ≥ 90 beats per minute (bpm) and initial SBP <100 mmHg (n = 34) had worse New York Heart Association functional class (p = 0.04), lower cardiac output (p = 0.02), and greater hyponatremia (p < 0.001). These patients were more likely to be hospitalized at the time of referral (p < 0.001) and more likely to have experienced

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“…The suppression of diurnal heart rate fluctuations in CHF patients results in reduced differences between minimal and maximal HR values as well as an increase in resting heart rate (3,18). Numerous studies (CIBIS-II, MERIT-HF, COMET and SHIFT) have demonstrated a relationship among increased resting heart rate, mortality and health-related quality of life (2,(19)(20)(21)(22).…”

Section: Discussionmentioning

confidence: 99%

A new approach to the measurement of heart rate in patients with chronic heart failure-Heart rate performance index: an observational study

Akyüz

Alpsoy²,

Akkoyun³

et al. 2013

AnadoluKardiyolDerg

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Objective: In order to evaluate the utility of the heart rate performance index (HRPI), which is obtained by dividing HR mean by the difference of HR max and HR min in the context of Holter monitoring, we sought to determine whether there was any correlation or relationship between the HRPI and LVEF values as determined by echocardiography and to compare the HRPI between the study and control groups. Methods: This study is a cross-sectional, controlled observational study. Thirty-two patients with symptomatic or asymptomatic left ventricular systolic dysfunction (LVEF <45%) were included as study group and 32 subjects without chronic heart failure (CHF) were included as a control group. In the study group, 10 patients were in NYHA class I (31.2%), 12 -were in NYHA class II (37.6%) and 10 -were in NYHA class III (31.2%). Heart rate analysis was measured using 24-hour Holter ambulatory electrocardiography. To determine the HRPI, the difference between maximum (HR max) and minimum heart rate (HR min) was divided by mean heart rate (HR mean) (beats/minute): HRPI=(HR max-HR min) / HR mean. Statistical analysis was performed using t-test for independent samples, Mann-Whitney U test, Chi-square test, Kruskal-Wallis test, Pearson's correlation and linear regression analyses. Results: The HRPI index value was markedly decreased [0.83 (0.58-1.1) and 1.10 (0.74-1.3), p<0.001] in the study group as compared to the control group. The data collected for the study group and the control group (n=64) demonstrated a positive correlation between the HRPI and LVEF (r=0.62, p<0.001) as well as a negative correlation between the HR mean and LVEF (r=-0.39, p<0.003). The HR mean was higher (80.2±11.3 and 75.2±6.7, p<0.007) and HR max-HR min (67.9±11.6 and 83.3±14.3, p<0.001) were lower in the study group as compared to the control group. Linear regression analysis demonstrated no significant relationship between LVEF and HRPI and other heart rate derivatives (unstandardized β=42.43 95% CI: 21.98-50.51, p=0.231). Conclusion: According to our findings, patients with CHF exhibited higher HR mean values, reduced HR max-min values and significantly decreased HRPI values. There is a positive correlation between HRPI and LVEF, a decreased HRPI is associated with a decreased LVEF, but there is no relationship between these two variables. Therefore HRPI values may represent a viable option for assessing daily exercise activity and potentially sympathetic activation in patients with CHF. The assessment of HRPI may be helpful the evaluation of CHF patients, as well as resting HR. (Anadolu Kardiyol Derg 2013; 13: 215-20) Key words: Congestive heart failure, ambulatory electrocardiography, heart rates, ventricular ejection fraction, regression analysis

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Assessment of autonomic tone over a 24-hour period in patients with congestive heart failure: Relation betweeen mean heart rate and measures of heart rate variability

Cited by 55 publications

References 28 publications

Role of Circadian Rhythmicity in the Heart Rate Variability Preceding Non-Sustained Ventricular Tachycardia

Role of Circadian Rhythmicity in the Heart Rate Variability Preceding Non-Sustained Ventricular Tachycardia

Initial Heart Rate and Systolic Blood Pressure Predict Outcomes in Chronic Heart Failure Patients who are Evaluated for Cardiac Transplant

A new approach to the measurement of heart rate in patients with chronic heart failure-Heart rate performance index: an observational study

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