Assessment of axonal sprouting and motor performance after hypoglossal–facial end-to-side nerve repair: experimental study in rats

Sarıkcıoğlu, Levent; Hizay, Arzu; Özsoy, Umut; Kandemir, Yasemin Behram; Şekerci, Rahime; Angelov, Doychin N.

doi:10.1007/s00221-020-05835-6

Cited by 2 publications

(1 citation statement)

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“…The hypoglossal nerve is primarily a motor nerve that innervates the intrinsic and extrinsic muscles of the tongue. 46 Similar to spinal accessory nerve model, hypoglossal nerve model can be used for the facial nerve transfer studies [45][46][47] as well as hypoglossal nerve stimulation or tongue strength studies. 48 Due to its anatomical location, the hypoglossal nerve can be exposed using similar techniques for exposure of the facial nerve.…”

Section: Hypoglossal Nervementioning

confidence: 99%

Experimental Cranial Nerve Models in the Rat

Karagoz,

Zhang,

Chaker

et al. 2024

J Reconstr Microsurg

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Background The intricacies of nerve regeneration following injury have prompted increased research efforts in recent years, with a primary focus on elucidating regeneration mechanisms and exploring various surgical techniques. While many experimental animals have been used for these investigations, the rat continues to remain the most widely used model due to its cost-effectiveness, accessibility, and resilience against diseases and surgical/anesthetic complications. A comprehensive evaluation of all the experimental rat models available in this context is currently lacking. Methods We summarize rat models of cranial nerves while furnishing descriptions of the intricacies of achieving optimal exposure. Results This review article provides an examination of the technical exposure, potential applications, and the advantages and disadvantages inherent to each cranial nerve model. Conclusion Specifically in the context of cranial nerve injury, numerous studies have utilized different surgical techniques to expose and investigate the cranial nerves in the rat.

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Section: Hypoglossal Nervementioning

confidence: 99%