Benefits of
Glycyrrhiza uralensis
include removing heat, detoxifying, and moistening the lungs, easing coughs, refueling the spleen, and balancing medications. In addition to providing theoretical guidance for the development of the
G. uralensis
industry and rural revitalization plan, it is anticipated that this paper will also provide basic data for the formulation of production layout of the
G. uralensis
industry at the county level, the control of cultivation industry direction, the establishment of high-quality
G. uralensis
cultivation technology system. The Maximum Entropy (MaxEnt) model was used to simulate the potential distribution of
G. uralensis
, a Chinese medicine resource, in Naiman Banner. By conducting a field inquiry and a broad assessment of the available Chinese medicine resources, the distribution information was acquired. The random forest technique was used to classify
G. uralensis
. The phenological cycle and development mode of vegetation, which exhibits diverse temporal traits and aids in identification, were elucidated through long-term series analysis. The random forest classification algorithm based on multiple features showed high accuracy in remote sensing (RS) recognition of
G. uralensis
. Comparative analysis of the MaxEnt and RS results showed that the planting area of
G. uralensis
was smaller than that of its potential distribution. The expansion to high-suitability areas planting should be prioritized. Based on the dual analysis of regional and remote sensing, it not only proved the great potential of using geographic information to predict the distribution of
G. uralensis
, but also verified the great potential of extracting the distribution of
G. uralensis
from GF-6 images. These results will guide the planting and development of
G. uralensis
in Naiman Banner and a scientific basis for the development of
G. uralensis
economy, conducive to optimizing the ecological environment and promoting rural revitalization programs.